Evidence map›Paper›PMID 39261751›Full record

ArticleBMC gastroenterology2024

A modified GLIM criteria-based nomogram for the survival prediction of gastric cancer patients undergoing surgical resection.

Xi Luo, Bin Cai, Weiwei Jin

Abstract read
In one paragraph

Article in BMC gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Xi LuoDepartment of Clinical Nutrition, Tongde Hospital of Zhejiang Province, Hangzhou, 310012, China. luoxi0571@sina.com.
Bin CaiSir Run Run Shaw Hospital, Zhejiang University School of Medicine, Hangzhou, 310016, China. caibin@zju.edu.cn.
Weiwei JinDepartment of Clinical Nutrition, Tongde Hospital of Zhejiang Province, Hangzhou, 310012, China.

Funding

Chinese Medicine Research Program of Zhejiang Province 2024ZL 349Medical Science and Technology Project of Zhejiang Province 2023KY360Research Fund Project of Zhejiang Nutrition Society ZN-YCHP-2023-005
6 · The paper itself

Abstract

backgroundThis study aimed to develop a comprehensive model based on five GLIM variables to predict the individual survival and provide more appropriate patient counseling.

methodsThis retrospective cohort study included 301 gastric cancer (GC) patients undergoing radical resection. C-reactive protein (CRP) as an inflammatory marker was included in GLIM criteria and a nomogram for predicting 5-year overall survival (OS) in GC patients was established. The Bootstrap repeated sampling for 1000 times was used for internal validation.

resultsOf the total 301 patients, 20 (6.64%) died within 5 years. CRP improved the sensitivity and accuracy of the survival prediction model (AUC = 0.782, 0.694 to 0.869 for the model without CRP; AUC = 0.880, 0.809 to 0.950 for the model adding CRP). Besides, a GLIM-based nomogram was established with an AUC of 0.889. The C-index for predicting OS was 0.878 (95% CI: 0.823 to 0.934), and the calibration curve fitted well. Decision curve analysis (DCA) showed the clinical utility of the nomogram based on GLIM.

conclusionThe addition of CRP improved the sensitivity and accuracy of the survival prediction model. The 5-year survival probability of GC patients undergoing radical resection can be reliably predicted by the nomogram presented in this study.

Indexed as

C-Reactive ProteinNomogramsStomach NeoplasmsAdultAgedFemaleGastrectomyHumansMaleMiddle AgedPrognosisRetrospective StudiesSensitivity and SpecificitySurvival AnalysisC-Reactive ProteinC-reactive proteinGastric cancerGLIMMalnutritionOverall survivalPrediction

Identifiers

PMID39261751
PMCPMC11389597

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.