ArticleEye (London, England)2024
Clinical features, risk factors and outcomes of contact lens-related bacterial keratitis in Nottingham, UK: a 7-year study.
Article in Eye (London, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed.
- Infectious bacterial keratitis management in a Swedish region: Risk factors, treatment and time-to-resolution.Acta ophthalmologica · 2026Article
- Contact Lens-Associated Ocular Surface and Corneal Disorders.Methods and protocols · 2026Review
- Bacterial and fungal keratitis in Northeast Mexico: demographic, predisposing, and microbiological differences among non-contact lens, optical contact lens, and bandage contact lens wearers.International ophthalmology · 2026Observational
- Contact lens-related versus non-contact lens-relatedFrontiers in medicine · 2026Article
- Photodynamic Antibacterial Nanofibers with Tunable Pro- and Antioxidant Activity via N,S-Doped Carbon Quantum Dots for Corneal Tissue Engineering.ACS applied materials & interfaces · 2025Article
- Emerging Ocular Pathogen Resistance and Clinically Used Solutions: A Problem That Is More than Meets the Eye.Pharmaceuticals (Basel, Switzerland) · 2025Review
- Pseudomonas aeruginosa keratitis in a tertiary referral center: a decade of clinical insights and therapeutic challenges.Journal of ophthalmic inflammation and infection · 2025Article
- Biosynthetic ε-poly-L-lysine for the treatment of extensively- and pan-drug-resistant Pseudomonas aeruginosa.npj antimicrobials and resistance · 2025Article
- Five-Year Analysis of Microbial Keratitis Incidence, Isolates, and In Vitro Antimicrobial Sensitivity in the South West of England: An Epidemiological Study.Microorganisms · 2025Article
- Infectious keratitis in Western New York: a 10-year review of patient demographics, clinical management, and treatment failure.Frontiers in ophthalmology · 2024Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
BACKGROUND/
objectivesTo examine the clinical characteristics, risk factors and outcomes of contact lens-related bacterial keratitis (CLBK) in a large UK tertiary referral centre. SUBJECTS/
methodsA retrospective analysis of all patients who presented to the Queen's Medical Centre, Nottingham, UK, with suspected CLBK between October 2015 to September 2022 (a 7-year period) was performed. Relevant data on demographic factors, CL wear behaviour, causes, clinical characteristics, and outcomes were analysed.
resultsWe included 138 patients with CLBK; the mean age was 42.0 ± 17.8 years and 74 (53.6%) patients were male. Most CLBK were related to soft CL wear (94.5%), particularly monthly disposable (42.5%) and daily disposable (24.4%) CLs. Poor CL wear behaviour/hygiene was documented in 57.1% cases. Among the 64 (46.4%) microbiological-positive cases (n = 73 organisms), Pseudomonas aeruginosa (36, 49.3%) and Staphylococcus spp. (16, 21.9%) were most commonly identified. Six (4.3%) cases were polymicrobial. Most (97.0%) patients were successfully treated with topical antibiotics alone, with 80.6% achieving good final corrected-distance-visual-acuity (CDVA) of ≥ 0.30 logMAR. Poor visual outcome (final CDVA < 0.30 logMAR) was significantly associated with presenting CDVA < 0.6 logMAR (p = 0.002) and central ulcer (p = 0.004). Poor corneal healing (complete healing of > 30 days from initial presentation) was significantly associated with age > 50 years (p = 0.028), female gender (p = 0.020), and infiltrate size >3 mm (p = 0.031).
conclusionsPoor CL wear behaviour/hygiene is commonly observed in CLBK, highlighting the importance of improved counselling and awareness regarding CL use and hygiene. When presented early and managed appropriately, most patients are able to achieve good clinical outcomes with medical treatment alone.
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