Evidence map›Paper›PMID 39261149›Full record

ArticleHematology, transfusion and cell therapy

Lower doses of dacarbazine (modified BEACODD) as a safer strategy with equal effectiveness in an intensive treatment protocol of Hodgkin's lymphoma: a preliminary retrospective analysis of a single public center in Brazil.

Larissa Hilario Dulley, Arthur Gomes Oliveira Braga, Guilherme Garcia Rodrigues, Sergio Costa Fortier, Carlos Sérgio Chiattone, Talita Maira Bueno da Silveira

Abstract read
In one paragraph

Article in Hematology, transfusion and cell therapy. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Larissa Hilario DulleyIrmandade de Santa Casa de Misericórdia de São Paulo, São Paulo, SP, Brazil.
Arthur Gomes Oliveira BragaA.C. Camargo Cancer Center, São Paulo, SP, Brazil. Electronic address: arthur_brg@hotmail.com.
Guilherme Garcia RodriguesIrmandade de Santa Casa de Misericórdia de São Paulo, São Paulo, SP, Brazil.
Sergio Costa FortierIrmandade de Santa Casa de Misericórdia de São Paulo, São Paulo, SP, Brazil.
Carlos Sérgio ChiattoneIrmandade de Santa Casa de Misericórdia de São Paulo, São Paulo, SP, Brazil.
Talita Maira Bueno da SilveiraIrmandade de Santa Casa de Misericórdia de São Paulo, São Paulo, SP, Brazil; A.C. Camargo Cancer Center, São Paulo, SP, Brazil.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The German Hodgkin Study Group developed the escalated BEACOPP (bleomycin, etoposide, doxorubicin, cyclophosphamide, vincristine, procarbazine, and prednisone) protocol as a treatment strategy for advanced-stage Hodgkin's lymphoma. In Brazil, as well as in other countries, procarbazine has been replaced with dacarbazine due to the limited availability of procarbazine. The Hematology Center at Irmandade da Santa Casa de Misericórdia in São Paulo adopted and modified the escalated BEACOPP protocol, substituting prednisone with dexamethasone and incorporating two different doses of dacarbazine: 375 mg/m

Indexed as

Advanced diseaseDacarbazineHodgkin lymphoma

Identifiers

PMID39261149
PMCPMC12011110

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.