Evidence map›Paper›PMID 39261008›Full record

ArticleThe Journal of neuroscience : the official journal of the Society for Neuroscience2024

Xinying Guo, Shangzhou Xia, Tenghuan Ge, Yangtao Lin, Shirley Hu, Haijian Wu, Xiaochun Xie, Bangyan Zhang, Sonia Zhang, Jianxiong Zeng and 5 more

Abstract read
In one paragraph

Article in The Journal of neuroscience : the official journal of the Society for Neuroscience, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 31 papers.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

31 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Review
  5. Review
  6. Chemogenetic modulation of CNS pericytes: Impact on pericyte CaMolecular therapy : the journal of the American Society of Gene Therapy · 2026
    Article
  7. Review
  8. Review
  9. Article
  10. Review
  11. Article
  12. Review
  13. Article
  14. Article
  15. Eppur si muove: the dynamic brain pericyte.Fluids and barriers of the CNS · 2025
    Review
  16. Article
  17. Article
  18. Systemic nimodipine affects pericyte calcium signaling, resting hemodynamics and neurovascular coupling in healthy mouse brain.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2025
    Article
  19. Pericytes in tissue fibrosis.American journal of physiology. Cell physiology · 2025
    Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Xinying GuoCenter for Neurodegeneration and Regeneration, Zilkha Neurogenetic Institute and Department of Physiology and Neuroscience, Keck School of Medicine, University of Southern California, Los Angeles, California 90033 sarah_guoxy@163.com qma@llu.edu zzhao@usc.edu.
Shangzhou XiaCenter for Neurodegeneration and Regeneration, Zilkha Neurogenetic Institute and Department of Physiology and Neuroscience, Keck School of Medicine, University of Southern California, Los Angeles, California 90033.
Tenghuan GeCenter for Neurodegeneration and Regeneration, Zilkha Neurogenetic Institute and Department of Physiology and Neuroscience, Keck School of Medicine, University of Southern California, Los Angeles, California 90033.
Yangtao LinDepartment of Basic Sciences, The Lawrence D. Longo, MD Center for Perinatal Biology, Loma Linda University School of Medicine, Loma Linda, California 92350.ORCID 0009-0002-3805-9764
Shirley HuDepartment of Basic Sciences, The Lawrence D. Longo, MD Center for Perinatal Biology, Loma Linda University School of Medicine, Loma Linda, California 92350.
Haijian WuCenter for Neurodegeneration and Regeneration, Zilkha Neurogenetic Institute and Department of Physiology and Neuroscience, Keck School of Medicine, University of Southern California, Los Angeles, California 90033.
Xiaochun XieCenter for Neurodegeneration and Regeneration, Zilkha Neurogenetic Institute and Department of Physiology and Neuroscience, Keck School of Medicine, University of Southern California, Los Angeles, California 90033.
Bangyan ZhangCenter for Neurodegeneration and Regeneration, Zilkha Neurogenetic Institute and Department of Physiology and Neuroscience, Keck School of Medicine, University of Southern California, Los Angeles, California 90033.
Sonia ZhangCenter for Neurodegeneration and Regeneration, Zilkha Neurogenetic Institute and Department of Physiology and Neuroscience, Keck School of Medicine, University of Southern California, Los Angeles, California 90033.
Jianxiong ZengCenter for Neurodegeneration and Regeneration, Zilkha Neurogenetic Institute and Department of Physiology and Neuroscience, Keck School of Medicine, University of Southern California, Los Angeles, California 90033.
Jian-Fu ChenCenter for Craniofacial Molecular Biology, University of Southern California, Los Angeles, California 90033.
Axel MontagneCentre for Clinical Brain Sciences, UK Dementia Research Institute at University of Edinburgh, Edinburgh EH16 4SB, United Kingdom.
Fan GaoCaltech Bioinformatics Resource Center, California Institute of Technology, Pasadena, California 91125.
Qingyi MaDepartment of Basic Sciences, The Lawrence D. Longo, MD Center for Perinatal Biology, Loma Linda University School of Medicine, Loma Linda, California 92350 sarah_guoxy@163.com qma@llu.edu zzhao@usc.edu.
Zhen ZhaoCenter for Neurodegeneration and Regeneration, Zilkha Neurogenetic Institute and Department of Physiology and Neuroscience, Keck School of Medicine, University of Southern California, Los Angeles, California 90033 sarah_guoxy@163.com qma@llu.edu zzhao@usc.edu.ORCID 0000-0001-8967-5570

Funding

Understanding Neural Bases for Neuropsychiatric Impairments in Alzheimer's Disease ModelsR01AG089756 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI Huizhong Whit Tao, Zhen Zhao · 2024 to 2026
$3.6M
The role of ATP13A5 ATPase in determining blood-brain pericyte functionsRF1NS135617 · NINDS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ZHAO, ZHEN · 2023 to 2023
$2.4M
A TIMEM252-dependent Microvascular Endophenotype in Alzheimer’s DiseaseRF1NS122060 · NINDS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ZHAO, ZHEN · 2021 to 2021
$2.3M
Pericyte-neuronal crosstalk in health and Alzheimer's DiseaseR01AG061288 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ZHAO, ZHEN · 2019 to 2023
$2.1M
The protective effects of c-type natriuretic peptide in the neonatal brainR01NS112404 · NINDS · LOMA LINDA UNIVERSITY · PI MA, QINGYI · 2019 to 2023
$1.7M
A TIMEM252-dependent Microvascular Endophenotype in Alzheimer’s DiseaseR01NS122060 · NINDS · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ZHAO, ZHEN · 2024 to 2025
$1.5M
Chemogenetic Mouse Models for Cerebral Hypoperfusion and VCIDR61NS137365 · NINDS · SEATTLE CHILDREN'S HOSPITAL · PI SHIH, ANDY Y, ZHAO, ZHEN · 2024 to 2025
$1.3M
Probing the heterogeneity of brain pericytes using new genetic toolsR21AG085559 · NIA · UNIVERSITY OF SOUTHERN CALIFORNIA · PI ZHAO, ZHEN · 2024 to 2025
$456k
MicroRNA210 and neuroinflammation in acute brain injury of ischemic StrokeR21NS126583 · NINDS · LOMA LINDA UNIVERSITY · PI MA, QINGYI · 2023 to 2023
$443k
NIA NIH HHS R01 AG061288NIA NIH HHS R01 AG089756NIA NIH HHS R21 AG085559NINDS NIH HHS R01 NS112404NINDS NIH HHS R01 NS122060NINDS NIH HHS R21 NS126583NINDS NIH HHS R61 NS137365NINDS NIH HHS RF1 NS122060NINDS NIH HHS RF1 NS135617
6 · The paper itself

Abstract

Perivascular mural cells including vascular smooth cells (VSMCs) and pericytes are integral components of the vascular system. In the central nervous system (CNS), pericytes are also indispensable for the blood-brain barrier (BBB), blood-spinal cord barrier, and blood-retinal barrier and play key roles in maintaining cerebrovascular and neuronal functions. However, the functional specifications of pericytes between CNS and peripheral organs have not been resolved at the genetic and molecular levels. Hence, the generation of reliable CNS pericyte-specific models and genetic tools remains very challenging. Here, we report a new CNS pericyte marker in mice. This putative cation-transporting ATPase 13A5 (

Indexed as

Central Nervous SystemPericytesAnimalsBiomarkersBlood-Brain BarrierBrainFemaleMaleMiceMice, Inbred C57BLMice, TransgenicRetinaSpinal CordBiomarkersblood–brain barrierdevelopmentmouse modelmural cellspericytesingle-cell transcriptomics

Identifiers

PMID39261008
PMCPMC11502228

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.