Evidence map›Paper›PMID 39261005›Full record

ArticleMethods in enzymology2024

Development of a rapid mass spectrometric method for the analysis of ten-eleven translocation enzymes.

Clara Graves, Kabirul Islam

Abstract read
In one paragraph

Article in Methods in enzymology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Clara GravesDepartment of Chemistry, University of Pittsburgh, Pittsburgh, PA, United States.
Kabirul IslamDepartment of Chemistry, University of Pittsburgh, Pittsburgh, PA, United States. Electronic address: kai27@pitt.edu.

Funding

Crosslinking-Assisted Substrate Identification for Lysine DemethylasesR01GM130752 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI ISLAM, KABIRUL · 2020 to 2023
$1.2M
National Science Foundation CHE-2204114NIGMS NIH HHS R01 GM130752
6 · The paper itself

Abstract

In DNA, methylation at the fifth position of cytosine (5mC) by DNA methyltransferases is essential for eukaryotic gene regulation. Methylation patterns are dynamically controlled by epigenetic machinery. Erasure of 5mC by Fe

Indexed as

5-MethylcytosineDioxygenasesDNA-Binding ProteinsProto-Oncogene ProteinsCytosineDNA MethylationEnzyme AssaysHumansMixed Function OxygenasesOxidation-ReductionSpectrometry, Mass, Matrix-Assisted Laser Desorption-Ionization5-carboxycytosine5-formylcytosine5-hydroxymethylcytosine5-MethylcytosineCytosineDioxygenasesDNA-Binding ProteinsMixed Function OxygenasesProto-Oncogene ProteinsTET1 protein, humanTET2 protein, humanTET3 protein, humanBase-resolution sequencingBisulfite SequencingDNA demethylationDNA methylationEpigeneticsMALDI-TOF mass spectrometryTET enzymes

Identifiers

PMID39261005
PMCPMC12690557

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.