Evidence map›Paper›PMID 39260886›Full record

ArticleLife science alliance2024

Novel imaging tools to study mitochondrial morphology in

Miriam Valera-Alberni, Pallas Yao, Silvia Romero-Sanz, Anne Lanjuin, William B Mair

Abstract read
In one paragraph

Article in Life science alliance, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
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  4. Induction and regulation of a reversible form of suspended animation inbioRxiv : the preprint server for biology · 2026
    Article
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  6. Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Miriam Valera-AlberniDepartment of Molecular Metabolism, Harvard TH Chan School of Public Health, Boston, MA, USA.ORCID 0000-0002-1144-573X
Pallas YaoDepartment of Molecular Metabolism, Harvard TH Chan School of Public Health, Boston, MA, USA.
Silvia Romero-SanzDepartment of Molecular Metabolism, Harvard TH Chan School of Public Health, Boston, MA, USA.
Anne LanjuinDepartment of Molecular Metabolism, Harvard TH Chan School of Public Health, Boston, MA, USA.
William B MairDepartment of Molecular Metabolism, Harvard TH Chan School of Public Health, Boston, MA, USA wmair@hsph.harvard.edu.ORCID 0000-0002-0661-1342

Funding

Mechanisms Specific to the Beneficial Effects of Dietary RestrictionR01AG044346 · NIA · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI William B Mair · 2013 to 2026
$3.8M
Reversing Loss of Metabolic Homeostasis to Ameliorate Alzheimer's Disease PathogenicityR01AG067106 · NIA · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI MAIR, WILLIAM B · 2020 to 2024
$2.0M
Defining Functional Outputs of Mitochondrial Networks in LongevityR21AG056930 · NIA · HARVARD SCHOOL OF PUBLIC HEALTH · PI MAIR, WILLIAM B · 2018 to 2019
$438k
Mechanisms of Intermittent Fasting and Longevity in C. elegansF31AG066458 · NIA · HARVARD SCHOOL OF PUBLIC HEALTH · PI YAO, PALLAS · 2019 to 2022
$108k
NIA NIH HHS F31 AG066458NIA NIH HHS R01 AG044346NIA NIH HHS R01 AG067106NIA NIH HHS R21 AG056930
6 · The paper itself

Abstract

Mitochondria exhibit a close interplay between their structure and function. Understanding this intricate relationship requires advanced imaging techniques that can capture the dynamic nature of mitochondria and their impact on cellular processes. However, much of the work on mitochondrial dynamics has been performed in single celled organisms or in vitro cell culture. Here, we introduce novel genetic tools for live imaging of mitochondrial morphology in the nematode

Indexed as

Caenorhabditis elegansMitochondriaAnimalsMitochondrial Dynamics

Identifiers

PMID39260886
PMCPMC11391045

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.