Observational studyBMJ open2024
Regional wall motion abnormalities on focused transthoracic echocardiography in patients presenting with acute chest pain: a predefined post hoc analysis of the prospective single-centre observational EPIC-ACS study.
Observational study in BMJ open, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03787797 (Epicardial Adipose Tissue Thickness PredIcts Obstructive Coronary Artery Disease in Acute Coronary Syndrome Patients), which is not on this map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Epicardial Adipose Tissue Thickness PredIcts Obstructive Coronary Artery Disease in Acute Coronary Syndrome Patients
Who cites it
5 citing papers in PubMed.
- Ejection fraction and absolute delta troponin in the early emergency department assessment of high coronary disease burden in NSTEMI patients: a retrospective observational study.BMC emergency medicine · 2026Observational
- Can FoCUS Speed Up the Management of Acute Coronary Syndrome in the Emergency Department?Medicina (Kaunas, Lithuania) · 2026Review
- Artificial intelligence implementation in automated heart chambers quantification during pharmacological stress echocardiography.European heart journal. Digital health · 2026Article
- Cardiac CT in Non-Obstructive Coronary Artery Disease (NOCAD): A Literature Review.Journal of clinical medicine · 2025Review
- AI-guided refinement of coronary revascularization need in patients suspected of acute coronary syndrome.European heart journal. Digital health · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
10 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesWe evaluated the ability of the assessment of regional wall motion abnormalities (RWMA) detected via transthoracic echocardiography to predict the presence of obstructive coronary artery disease (CAD) in patients presenting with acute chest pain to the emergency department.
designProspective single-centre observational study.
settingTertiary care university hospital emergency unit.
participantsPatients presenting to the emergency department with acute chest pain suggestive of obstructive CAD. PRIMARY OUTCOME MEASURE: The primary endpoint was defined as the presence of obstructive CAD, requiring revascularisation therapy.
resultsOverall, 657 patients (age 58.1±18.0 years, 53% men) were included in our study. RWMA were detected in 76 patients (11.6%). RWMA were significantly more frequent in patients reaching the primary endpoint (26.2% vs 7.6%, p<0.001). In multivariable regression analysis, the presence of RWMA was associated with threefold increased odds of the presence of obstructive CAD (3.41 (95% CI 1.99 to 5.86), p<0.001). Adding RWMA to a multivariable model of the Thrombolysis in Myocardial Infarction (TIMI) risk score, cardiac biomarkers and traditional risk factors significantly improved the area under the curve for prediction of obstructive CAD (95% CI 0.777 to 0.804, p=0.0092).
conclusionRWMA strongly and independently predicts the presence of obstructive CAD in patients presenting with acute chest pain to the emergency department.
trial registrationThe study has been registered online (NCT03787797).
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