ArticleActa psychiatrica Scandinavica2025
A national evaluation of a multi-modal, blended, digital intervention integrated within Australian youth mental health services.
Article in Acta psychiatrica Scandinavica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
19 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Effectiveness of eHealth Interventions in Alleviating Burden on Informal Caregivers of People With Dementia: Systematic Review and Meta-Analysis of Randomized Controlled Trials.Journal of medical Internet research · 2026Pooled it
- Moderated Online Social Therapy (MOST) in Help-Seeking Young People: Pilot Randomized Controlled Study.Journal of medical Internet research · 2025Trial
- Bridging gaps in youth mental health care: YOUTHreach-a comprehensive European strategy.European child & adolescent psychiatry · 2026Article
- Implementation of digital mental health interventions for children and adolescents: A systematic review.Internet interventions · 2026Review
- Youth supporting youth online: A content analysis of peer counselling at the online chat of @ease.Internet interventions · 2026Article
- The present and future of blended care: current research and introduction to the B-FIT framework.NPJ digital medicine · 2026Review
- Article
- Effectiveness and Experiences of Online Mental Health Peer Support for Young People: Systematic Scoping Review.JMIR mental health · 2026Review
- Digital Therapeutics and Blended Care in Major Depressive Disorder: Current Evidence and Future Directions.Advances in experimental medicine and biology · 2026Review
- Article
- Symptom heterogeneity in students with mild to severe depression symptomatology and their differential symptom-specific changes during an internet-based, guided cognitive behavioural therapy intervention.Internet interventions · 2025Article
- Insights from fifteen years of real-world development, testing and implementation of youth digital mental health interventions.Internet interventions · 2025Review
- User Character Strengths and Engagement Prediction on a Digital Mental Health Platform for Young People: Longitudinal Observational Study.Journal of medical Internet research · 2025Observational
- The evolving field of digital mental health: current evidence and implementation issues for smartphone apps, generative artificial intelligence, and virtual reality.World psychiatry : official journal of the World Psychiatric Association (WPA) · 2025Article
- A meta-analysis of persuasive design, engagement, and efficacy in 92 RCTs of mental health apps.NPJ digital medicine · 2025Article
- A national evaluation of a multi-modal, blended, digital intervention integrated within Australian youth mental health services.Acta psychiatrica Scandinavica · 2025Article
- National Implementation of Perinatal Mental Health Treatment-The MumSpace Digital Stepped-Care Model.International journal of environmental research and public health · 2025Article
- Article
- Exploring caregiver experiences with the altitudes digital mental health program: A thematic analysis.Digital healthArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
12 authors.
Funding
Abstract
backgroundYouth mental health (YMH) services have been established internationally to provide timely, age-appropriate, mental health treatment and improve long-term outcomes. However, YMH services face challenges including long waiting times, limited continuity of care, and time-bound support. To bridge this gap, MOST was developed as a scalable, blended, multi-modal digital platform integrating real-time and asynchronous clinician-delivered counselling; interactive psychotherapeutic content; vocational support; peer support, and a youth-focused online community. The implementation of MOST within Australian YMH services has been publicly funded.
objectiveThe primary aim of this study was to evaluate the real-world engagement, outcomes, and experience of MOST during the first 32 months of implementation.
methodYoung people from participating YMH services were referred into MOST. Engagement metrics were derived from platform usage. Symptom and satisfaction measures were collected at baseline, 6, and 12 (primary endpoint) weeks. Effect sizes were calculated for the primary outcomes of depression and anxiety and secondary outcomes of psychological distress and wellbeing.
resultsFive thousand seven hundred and two young people from 262 clinics signed up and used MOST at least once. Young people had an average of 19 login sessions totalling 129 min over the first 12 weeks of use, with 71.7% using MOST for at least 14 days, 40.1% for 12 weeks, and 18.8% for 24 weeks. There was a statistically significant, moderate improvement in depression and anxiety at 12 weeks as measured by the PHQ4 across all users irrespective of treatment stage (d = 0.41, 95% CI 0.35-0.46). Satisfaction levels were high, with 93% recommending MOST to a friend. One thousand one hundred and eighteen young people provided written feedback, of which 68% was positive and 31% suggested improvement.
conclusionsMOST is a highly promising blended digital intervention with potential to address the limitations and enhance the impact of YMH services.
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