Article in Journal of neurophysiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
2 · The registry
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Sarah C NudingDepartment of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, Florida, United States.ORCID 0009-0004-2035-8234
Lauren S SegersDepartment of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, Florida, United States.ORCID 0000-0003-1058-1569
Kimberly E IcemanDepartment of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, Florida, United States.ORCID 0000-0002-9004-3893
Russell O'ConnorDepartment of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, Florida, United States.
Jay B DeanDepartment of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, Florida, United States.ORCID 0000-0002-6474-0660
Pierina A ValarezoDepartment of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, Florida, United States.
Dale ShumanDepartment of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, Florida, United States.
Irene C SolomonDepartment of Physiology and Biophysics, Renaissance School of Medicine at Stony Brook University, Stony Brook, New York, United States.
Donald C BolserDepartment of Physiological Sciences, College of Veterinary Medicine, University of Florida, Gainesville, Florida, United States.ORCID 0000-0002-4577-8954
Kendall F MorrisDepartment of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, Florida, United States.
Bruce G LindseyDepartment of Molecular Pharmacology and Physiology, Morsani College of Medicine, University of South Florida, Tampa, Florida, United States.
Funding
Functional mapping of peripheral and central circuits for airway protection and breathingOT2OD023854 · OD · UNIVERSITY OF FLORIDA · PI BOLSER, DONALD C · 2016 to 2020
$10.8M
BRAINSTEM RESPIRATORY NEURON INTERACTIONSR01NS019814 · NINDS · UNIVERSITY OF SOUTH FLORIDA · PI LINDSEY, BRUCE G · 1985 to 2015
$3.6M
Brainstem Respiratory Neuron InteractionsR37NS019814 · NINDS · UNIVERSITY OF SOUTH FLORIDA · PI LINDSEY, BRUCE G · 2004 to 2010
$3.6M
Central and Peripheral Regulation of Laryngeal AdductionR01HL163008 · NHLBI · UNIVERSITY OF FLORIDA · PI BOLSER, DONALD C, PITTS, TERESA G · 2022 to 2025
$2.8M
Influence of Opioids on the Brainstem Respiratory NetworkR01HL155721 · NHLBI · UNIVERSITY OF FLORIDA · PI BOLSER, DONALD C, MORRIS, KENDALL FRANCIS · 2021 to 2024
$2.7M
MEDULLARY MECHANISMS OF HYPOXIC RESPIRATORY EXCITATIONR01HL063175 · NHLBI · STATE UNIVERSITY NEW YORK STONY BROOK · PI SOLOMON, IRENE C · 2000 to 2010
$2.6M
Computational Studies of the Respiratory BrainstemR01NS046062 · NINDS · UNIVERSITY OF SOUTH FLORIDA · PI LINDSEY, BRUCE G · 2002 to 2006
$2.1M
HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) HL155721HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) HL163008HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) HL63175HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS) NS19814HHS | NIH | National Institute of Neurological Disorders and Stroke (NINDS) NS46062HHS | NIH | OSC | Common Fund (NIH Common Fund) OT2OD023854NHLBI NIH HHS R01 HL063175NHLBI NIH HHS R01 HL155721NHLBI NIH HHS R01 HL163008NIH HHS OT2 OD023854NINDS NIH HHS R01 NS019814NINDS NIH HHS R01 NS046062NINDS NIH HHS R37 NS019814
6 · The paper itself
Abstract
Hypoxia can trigger a sequence of breathing-related behaviors, from augmentation to apneusis to apnea and gasping. Gasping is an autoresuscitative behavior that, via large tidal volumes and altered intrathoracic pressure, can enhance coronary perfusion, carotid blood flow, and sympathetic activity, and thereby coordinate cardiac and respiratory functions. We tested the hypotheses that hypoxia-evoked gasps are amplified through a disinhibitory microcircuit within the inspiratory neuron chain and that this drive is distributed via an efference copy mechanism. This generates coordinated gasplike discharges concurrently in other circuits of the raphe-pontomedullary respiratory network. Data were obtained from six decerebrate, vagotomized, neuromuscularly blocked, and artificially ventilated adult cats. Arterial blood pressure, phrenic nerve activity, end-tidal CO
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.
Hypoxia evokes a sequence of raphe-pontomedullary network operations for inspiratory drive amplification and gasping. · full record | OpenQuestion