Evidence map›Paper›PMID 39259484›Full record

ArticleJournal of nephrology2024

Association between pre-heart transplant kidney function and post-transplant outcomes in Black and White adults.

Ying Wei, Elizabeth Mostofsky, Francisco J Barrera, Lathan Liou, Soziema Salia, Martha Pavlakis, Murray A Mittleman

Abstract readComparative Study
PubMed Publisher
In one paragraph

Article in Journal of nephrology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Ying WeiDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, 677 Huntington Ave, Kresge 505-D, Boston, MA, 02215, USA.
Elizabeth MostofskyDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, 677 Huntington Ave, Kresge 505-D, Boston, MA, 02215, USA.
Francisco J BarreraDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, 677 Huntington Ave, Kresge 505-D, Boston, MA, 02215, USA.
Lathan LiouIcahn School of Medicine at Mount Sinai, New York, USA.
Soziema SaliaDepartment of Medicine, MedStar Union Memorial Hospital, Baltimore, USA.
Martha PavlakisHarvard Medical School, Boston, USA.
Murray A MittlemanDepartment of Epidemiology, Harvard T.H. Chan School of Public Health, 677 Huntington Ave, Kresge 505-D, Boston, MA, 02215, USA. mmittlem@hsph.harvard.edu.

Funding

Alcohol and Breast Cancer: Genetic Interactions and Effects on Aromatase Inhibitor TherapyK01AA027831 · NIAAA · HARVARD SCHOOL OF PUBLIC HEALTH · PI MOSTOFSKY, ELIZABETH · 2019 to 2023
$820k
NIAAA NIH HHS K01AA027831
6 · The paper itself

Abstract

backgroundIt remains unknown whether estimated glomerular filtration rate (eGFR) using the refit Chronic Kidney Disease Epidemiology Collaboration (CKD-EPI) equation without a term for race is associated with mortality and the need for kidney replacement therapy (KRT) differentially between Black and White heart transplant recipients.

methodsWe studied 25,900 adults included in the Scientific Registry of Transplant Recipients. We classified recipients into six categories of eGFR (< 30, 30 to < 45, 45 to < 60, 60 to < 90, 90 to < 120, ≥ 120 ml/min/1.73 m

resultsThe association between pre-transplant race-neutral eGFR and mortality varied by race (P

conclusionsWorsening pre-transplant eGFR using the new race-neutral CKD-EPI refit equation was associated with a higher rate of post-heart transplant mortality and KRT in Black and White recipients. The racial disparity in post-heart transplant mortality was narrower in the setting of severe kidney dysfunction.

Indexed as

Black or African AmericanGlomerular Filtration RateHeart TransplantationWhiteAdultAgedFemaleHumansKidneyMaleMiddle AgedRegistriesRenal Insufficiency, ChronicRenal Replacement TherapyRisk FactorsTreatment OutcomeGlomerular filtration rateHeart transplantationMortalityRace

Identifiers

PMID39259484

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.