Evidence map›Paper›PMID 39259331›Full record

ArticleJournal of neural transmission (Vienna, Austria : 1996)2025

Autonomic regulation and comorbid symptoms in children with attention deficit hyperactivity disorder.

Kira Kehm, Susan Schloß, Christopher Mann, Katja Becker, Udo König, Wilfried Pott, Mira-Lynn Chavanon, Ursula Pauli-Pott

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of neural transmission (Vienna, Austria : 1996), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Kira KehmDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Philipps-University of Marburg, Schützenstrasse 45, D-35039, Marburg, Germany.
Susan SchloßDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Philipps-University of Marburg, Schützenstrasse 45, D-35039, Marburg, Germany.
Christopher MannDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Philipps-University of Marburg, Schützenstrasse 45, D-35039, Marburg, Germany.
Katja BeckerDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Philipps-University of Marburg, Schützenstrasse 45, D-35039, Marburg, Germany.ORCID http://orcid.org/0000-0003-4858-5127
Udo KönigDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Philipps-University of Marburg, Schützenstrasse 45, D-35039, Marburg, Germany.
Wilfried PottDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Philipps-University of Marburg, Schützenstrasse 45, D-35039, Marburg, Germany.
Mira-Lynn ChavanonDepartment of Psychology, Philipps-University, Marburg, Germany.
Ursula Pauli-PottDepartment of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Philipps-University of Marburg, Schützenstrasse 45, D-35039, Marburg, Germany. Ursula.pauli-pott@med.uni-marburg.de.ORCID http://orcid.org/0000-0001-5980-7261

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveVagally-mediated heart rate variability (vmHRV) is regarded as transdiagnostic marker of emotion regulation and cognitive control capacity. We analysed vmHRV of children with attention deficit/hyperactivity disorder (ADHD). Based on previous research, we expected to find comorbid symptom dimensions (i.e. internalizing symptoms, conduct problems (CP), and callous unemotional (CU) traits) to relate to vmHRV measures.

methodsThe sample comprised 100 (70 boys) medication naïve children with ADHD. Children were 6 to 11 years old. High frequency HRV (HF-HRV) was measured at rest and during a delay of gratification task. Additionally, sympathetic reactivity was assessed via skin conductance responses (SCR). Comorbid symptoms were assessed by parent-report questionnaires and clinical interviews.

resultsThe multiple correlation between CU traits and the HF-HRV scores proved statistically significant. Higher CU traits were associated with higher HRV resting-state and response scores. CP were positively associated with the SCR score.

conclusionIn children with ADHD, increased CU traits might point to a comparatively less impaired self-regulation capacity in the reward-related context. The result corresponds to findings from previous studies. In the future, CU traits should be considered in analyses of autonomic regulation in ADHD.

Indexed as

Attention Deficit Disorder with HyperactivityAutonomic Nervous SystemConduct DisorderEmotional RegulationHeart RateChildComorbidityFemaleGalvanic Skin ResponseHumansMaleADHDAutonomic nerve systemCallous unemotional traitsHeart rate variabilityInternalizing symptomsLow prosocial emotionality

Identifiers

PMID39259331
PMCPMC11735537

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.