Evidence map›Paper›PMID 39259301›Full record

ArticlePediatric radiology2024

Impact of upgrading from a 25-cm to a 30-cm z-axis field of view digital PET/CT in a pediatric hospital.

Joseph G Meier, Andrew T Trout, Nadeen Abu Ata, Susan E Sharp, Christopher G Anton, Elanchezhian Somasundaram, Samuel L Brady

Abstract read
In one paragraph

Article in Pediatric radiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. A low-dose protocol in pediatricAnnals of nuclear medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Joseph G MeierDepartment of Radiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, MLC 5031, Cincinnati, OH, 45229, USA. joseph.meier@cchmc.org.ORCID 0000-0001-6794-9200
Andrew T TroutDepartment of Radiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, MLC 5031, Cincinnati, OH, 45229, USA.ORCID 0000-0003-1431-4054
Nadeen Abu AtaDepartment of Radiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, MLC 5031, Cincinnati, OH, 45229, USA.
Susan E SharpDepartment of Radiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, MLC 5031, Cincinnati, OH, 45229, USA.
Christopher G AntonDepartment of Radiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, MLC 5031, Cincinnati, OH, 45229, USA.
Elanchezhian SomasundaramDepartment of Radiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, MLC 5031, Cincinnati, OH, 45229, USA.ORCID 0000-0002-0440-5238
Samuel L BradyDepartment of Radiology, Cincinnati Children's Hospital Medical Center, 3333 Burnet Ave, MLC 5031, Cincinnati, OH, 45229, USA.ORCID 0000-0002-2785-4626

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundIncreased positron emission tomography (PET) scanner z-axis coverage provides an opportunity in pediatrics to reduce dose, anesthesia, or repeat scans due to motion.

objectiveRecently, our digital PET scanner was upgraded from a 25-cm to a 30-cm z-axis coverage. We compare the two systems through National Electrical Manufacturing Association (NEMA) testing and evaluation of paired images from patients scanned on both systems. MATERIALS AND

methodsNEMA testing and a retrospective review of pediatric patients who underwent clinically indicated 18F-fluorodeoxyglucose (FDG) PET computed tomography (PET/CT) on both systems with unchanged acquisition parameters were performed. Image quality was assessed with liver signal to noise ratio (SNR-liver) and contrast to noise ratio (CNR) in the thigh muscle and liver with results compared with an unpaired t-test. Three readers independently reviewed paired (25 cm and 30 cm) images from the same patient, blinded to scanner configuration.

resultsExpansion to 30 cm increased system sensitivity to 29.8% (23.4 cps/kBq to 30.4 cps/kBq). Seventeen patients (6 male/11 female, median age 12.5 (IQR 8.3-15.0) years, median weight 53.7 (IQR 34.2-68.7) kg) were included. SNR-liver and CNR increased by 35.1% (IQR 19.0-48.4%) and 43.1% (IQR 6.2-50.2%) (P-value <0.001), respectively. All readers preferred images from the 30-cm configuration. A median of 1 (IQR 1-1) for fewer bed positions was required with the 30-cm configuration allowing a median of 91 (IQR 47-136) s for shorter scans.

conclusionIncreasing z-axis coverage from 25 to 30 cm on a current-generation digital PET scanner significantly improved PET system performance and patient image quality, and reduced scan duration.

Indexed as

Hospitals, PediatricPositron Emission Tomography Computed TomographyRadiopharmaceuticalsAdolescentChildChild, PreschoolFemaleFluorodeoxyglucose F18HumansMaleRetrospective StudiesSensitivity and SpecificitySignal-To-Noise RatioFluorodeoxyglucose F18RadiopharmaceuticalsDecreased acquisition timeDecreased radiation doseIncreased PET sensitivityPediatricPositron emission tomography

Identifiers

PMID39259301
PMCPMC11473537

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.