ArticleThe Plant cell2024
The rice R2R3 MYB transcription factor FOUR LIPS connects brassinosteroid signaling to lignin deposition and leaf angle.
Article in The Plant cell, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Multi-environment genome-wide association study reveals genetic loci associated with drought tolerance during wheat germination.Plant cell reports · 2026Article
- PgZHD18-PgWDR5b increases basal thermotolerance in Physalis grisea by lignin biosynthesis dependent on H3K4me3.The Plant journal : for cell and molecular biology · 2026Article
- Spatiotemporal Metabolome and Single-Nucleus Transcriptome Integration Illuminates an Auxin Gradient Orchestrated by NtTAC1 Underlying Leaf Angle Regulation in Tobacco.Plant biotechnology journal · 2026Article
- Brassinosteroid signaling promotes stone cell lignification by enhancing nuclear accumulation of PbrBEH3 in pear fruit.The Plant journal : for cell and molecular biology · 2026Article
- Every angle covered: osWRKY36 regulates leaf inclination in rice.The Plant cell · 2026Article
- ZmDRL1 regulates maize leaf angle via phytohormone signaling.Plant cell reports · 2026Article
- Genome-wide analysis of the R2R3-MYB family reveals potential regulators of lignin and tricin metabolism in the model grass Setaria viridis.Molecular genetics and genomics : MGG · 2026Article
- Genome-Wide Identification, Characterization, Expression Analysis, and Interacting Protein Prediction of thePlants (Basel, Switzerland) · 2026Article
- Epidermal Cell Dynamics Regulates Rice Lamina Joint Morphogenesis and Leaf Angle Formation through OsZHD1 and OsZHD2 Regulation.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Article
- Comprehensive transcriptomic profiling identifies key regulatory genes mediating phytohormone signaling pathways during seed germination in Chenopodium quinoa.BMC genomics · 2026Article
- Activation of OsOxO2 by T-DNA Insertion Affects Plant Height and Leaf Angle in Rice.Rice (New York, N.Y.) · 2026Article
- Loci and natural alleles for leaf length and width revealed by a genome wide association study in adzuki bean.BMC plant biology · 2025Article
- Focus on Translational Research from Arabidopsis to Crop Plants and Beyond.The Plant cell · 2025Article
- Crucial Roles of Brassinosteroids in Cell Wall Composition and Structure Across Species: New Insights and Biotechnological Applications.Plant, cell & environment · 2025Review
- Overexpression ofFrontiers in plant science · 2025Article
- Structure, evolution, and roles of MYB transcription factors proteins in secondary metabolite biosynthetic pathways and abiotic stresses responses in plants: a comprehensive review.Frontiers in plant science · 2025Review
- Combined transcriptomic and metabolomic analysis of phenylpropanoid biosynthesis in the mechanism of leaf angle formation in Sorghum.Frontiers in plant science · 2025Article
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10 authors.
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Abstract
Leaf angle is an important agronomic trait for crop architecture and yield. In rice (Oryza sativa), the lamina joint is a unique structure connecting the leaf blade and sheath that determines leaf angle. Brassinosteroid (BR) signaling involving GLYCOGEN SYNTHASE KINASE-3 (GSK3)/SHAGGY-like kinases and BRASSINAZOLE-RESISTANT1 (BZR1) has a central role in regulating leaf angle in rice. In this study, we identified the atypical R2R3-MYB transcription factor FOUR LIPS (OsFLP), the rice homolog of Arabidopsis (Arabidopsis thaliana) AtFLP, as a participant in BR-regulated leaf angle formation. The spatiotemporal specificity of OsFLP expression in the lamina joint was closely associated with lignin deposition in vascular bundles and sclerenchyma cells. OsFLP mutation caused loose plant architecture with droopy flag leaves and hypersensitivity to BRs. OsBZR1 directly targeted OsFLP, and OsFLP transduced BR signals to lignin deposition in the lamina joint. Moreover, OsFLP promoted the transcription of the phenylalanine ammonia-lyase family genes OsPAL4 and OsPAL6. Intriguingly, OsFLP feedback regulated OsGSK1 transcription and OsBZR1 phosphorylation status. In addition, an Ala-to-Thr substitution within the OsFLP R3 helix-turn-helix domain, an equivalent mutation to that in Osflp-1, affected the DNA-binding ability and transcriptional activity of OsFLP. Our results reveal that OsFLP functions with OsGSK1 and OsBZR1 in BR signaling to maintain optimal leaf angle by modulating the lignin deposition in mechanical tissues of the lamina joint.
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