Evidence map›Paper›PMID 39258917›Full record

ArticleApplied and environmental microbiology2024

Transcriptomic characterization of recombinant

Santosh Kumar, Eric Agyeman-Duah, Marian M Awaga-Cromwell, Victor C Ujor

Abstract read
In one paragraph

Article in Applied and environmental microbiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Santosh KumarDepartment of Food Science, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Eric Agyeman-DuahDepartment of Food Science, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Marian M Awaga-CromwellDepartment of Food Science, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Victor C UjorDepartment of Food Science, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0002-5518-6530

Funding

Dairy Business Innovation AllianceDairy Innovation Hub AAK5475U.S. Department of Agriculture (USDA) WIS04018
6 · The paper itself

Abstract

Bioconversion of abundant lactose-replete whey permeate to value-added chemicals holds promise for valorization of this expanding food processing waste. Efficient conversion of whey permeate-borne lactose requires adroit microbial engineering to direct carbon to the desired chemical. An engineered strain of IMPORTANCE: Biological production of commodity chemicals from abundant waste streams such as whey permeate represents an opportunity for decarbonizing chemical production. Whey permeate remains a vastly underutilized feedstock for bioproduction purposes. Thus, enhanced understanding of the cellular and metabolic repertoires of lactose-mediated production of chemicals such as butanol promises to identify new targets that can be fine tuned in recombinant and native microbial strains to engender stronger coupling of whey permeate-borne lactose to value-added chemicals. Our results highlight new genetic targets for future engineering of

Indexed as

Clostridium beijerinckiiLactoseTranscriptomeBacterial ProteinsButanolsClostridiumMetabolic EngineeringWheyBacterial ProteinsButanolsLactosebutanol productionClostridium beijerinckiicysteine desaturaseiron uptakemethylglyoxalNAD biosynthesissignal transductiontranscriptomic analysis

Identifiers

PMID39258917
PMCPMC11497831

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.