Evidence map›Paper›PMID 39258808›Full record

ArticleChemSusChem2025

Unlocking Lignin's Potential: Engineered Bacterial Laccases to Produce Biologically Active Molecules.

Vânia Brissos, Márcia Rénio, Magdalena A Lejmel, Ricardo Estevinho, M Paula Robalo, M Rita Ventura, Lígia O Martins

Abstract read
In one paragraph

Article in ChemSusChem, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Vânia BrissosInstituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Av da República, Oeiras, 2780-157, Portugal.
Márcia RénioInstituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Av da República, Oeiras, 2780-157, Portugal.
Magdalena A LejmelInstituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Av da República, Oeiras, 2780-157, Portugal.
Ricardo EstevinhoInstituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Av da República, Oeiras, 2780-157, Portugal.
M Paula RobaloDepartamento de Engenharia Química, Instituto Superior de Engenharia de Lisboa, Instituto Politécnico de Lisboa, R. Conselheiro Emídio Navarro 1, Lisboa, 1959-007, Portugal.
M Rita VenturaInstituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Av da República, Oeiras, 2780-157, Portugal.
Lígia O MartinsInstituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Av da República, Oeiras, 2780-157, Portugal.

Funding

Fundação para a Ciência e a Tecnologia 2022. 02027.PTDCFundação para a Ciência e a Tecnologia AAC 01/SAICT/2016Fundação para a Ciência e a Tecnologia LA/P/0087/2020Fundação para a Ciência e a Tecnologia UIDB/04612/2020 and UIDP/04612/2020
6 · The paper itself

Abstract

Laccases are biocatalysts with immense potential in lignocellulose biorefineries to valorize emerging lignin monomers for sustainable chemicals. Despite reduced costs over the past two decades, enzymes remain a major expense in biorefining. Protein engineering can enhance enzyme properties and lower costs further. In this study, we used enzyme engineering tools to improve >400-fold the catalytic efficiency (k

Indexed as

BacteriaLaccaseLigninProtein EngineeringBiocatalysisHydrogen-Ion ConcentrationTemperatureLaccaseLigninBiocatalysisDirected evolutionLignans and neolignansLignin-related phenolicsNatural products

Identifiers

PMID39258808
PMCPMC11960585

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.