Evidence map›Paper›PMID 39258631›Full record

ArticleBrazilian oral research2024

Effect of adding arginine at different concentrations to experimental orthodontic resins: an in vitro study.

Ana Lídia Correa Santos, Lourenço Correr-Sobrinho, Fernanda Midori Tsuzuki, Anália Gabriela Facury Ferraz, José Guilherme Neves, Mário Alexandre Coelho Sinhoreti, Eduardo Martinelli Franco, Ana Rosa Costa

Abstract readEvaluation Study
In one paragraph

Article in Brazilian oral research, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ana Lídia Correa SantosFundação Hermínio Ometto, Department of Orthodontics, Araras, SP, Brazil.ORCID http://orcid.org/0000-0002-8100-9917
Lourenço Correr-SobrinhoUniversidade Estadual de Campinas - Unicamp, Piracicaba Dental School, Department of Restorative Dentistry, Piracicaba, SP, Brazil.ORCID http://orcid.org/0000-0002-2009-7407
Fernanda Midori TsuzukiUniversidade Estadual de Campinas - Unicamp, Piracicaba Dental School, Department of Restorative Dentistry, Piracicaba, SP, Brazil.ORCID http://orcid.org/0000-0001-8880-8036
Anália Gabriela Facury FerrazUniversidade Estadual de Campinas - Unicamp, Piracicaba Dental School, Department of Restorative Dentistry, Piracicaba, SP, Brazil.ORCID http://orcid.org/0000-0001-9255-3937
José Guilherme NevesUniversidade Estadual de Campinas - Unicamp, Piracicaba Dental School, Department of Restorative Dentistry, Piracicaba, SP, Brazil.ORCID http://orcid.org/0000-0003-1613-8496
Mário Alexandre Coelho SinhoretiUniversidade Estadual de Campinas - Unicamp, Piracicaba Dental School, Department of Restorative Dentistry, Piracicaba, SP, Brazil.ORCID http://orcid.org/0000-0002-1932-2902
Eduardo Martinelli FrancoUniversidade Estadual de Campinas - Unicamp, Piracicaba Dental School, Department of Microbiology, Piracicaba, SP, Brazil.ORCID http://orcid.org/0000-0001-5392-0167
Ana Rosa CostaFundação Hermínio Ometto, Department of Orthodontics, Araras, SP, Brazil.ORCID http://orcid.org/0000-0002-1020-3210

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The aim of this study was to assess the effect of adding arginine at different concentrations to commercial and experimental orthodontic resins on shear bond strength (SBS), as well as on the antimicrobial activity of arginine against S. mutans. Metal brackets were bonded onto the surface of 120 bovine incisors using Transbond, OrthoCem, and an experimental resin (ER), adding 0, 2.5, 5, and 7 wt.% of arginine. The SBS test was performed in deionized water at 37 ºC for 24 h, at 0.5 mm/min. SBS test results were subjected to two-way ANOVA and Tukey's test (α = 0.05). CFU/mL data (antimicrobial assessment) were assessed by Kruskal-Wallis and Dunn's tests (α = 0.05). No statistical difference between the resins was observed in untreated groups (p > 0.05). The addition of arginine at 2.5% (27.7 MPa) and 5% (29.0 MPa) increased the SBS of Transbond when compared (p < 0.05) to OrthoCem (18.5 and 15.6 MPa, respectively) and ER (16.3 and 18.1 MPa, respectively). Arginine at 7% improved the SBS of Transbond (24.1 MPa) and ER (21.0 MPa), which was statistically higher (p < 0.05) than OrthoCem (12.6 MPa). OrthoCem did not show a statistically significant difference at the three concentrations of arginine (p > 0.05). The addition of arginine to resins reduced the count of S. mutans (p < 0.05). As for ER, all concentrations of arginine significantly decreased CFU/mL (p < 0.05). Among commercial resins, only 7% of arginine significantly reduced CFU/mL. The addition of arginine did not interfere with the bond strength and demonstrated antibacterial activity against S. mutans.

Indexed as

ArginineMaterials TestingOrthodontic BracketsResin CementsShear StrengthStreptococcus mutansAnalysis of VarianceAnimalsBisphenol A-Glycidyl MethacrylateCattleDental BondingReference ValuesReproducibility of ResultsStatistics, NonparametricSurface PropertiesTime FactorsArginineBisphenol A-Glycidyl MethacrylateResin CementsTransbond

Identifiers

PMID39258631
PMCPMC11376598

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.