Evidence map›Paper›PMID 39258462›Full record

ArticleCancer medicine2024

A video intervention to improve patient understanding of tumor genomic testing in patients with cancer.

Deloris J Veney, Lai Y Wei, Amanda E Toland, Carolyn J Presley, Heather L Hampel, Tasleem J Padamsee, Clara N Lee, William J Irvin, Michael J Bishop, James J Kim and 3 more

Abstract read
In one paragraph

Article in Cancer medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

13 authors.

Deloris J VeneyDivision of Medical Oncology, Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA.
Lai Y WeiDepartment of Biomedical Informatics, Ohio State University, Columbus, Ohio, USA.
Amanda E TolandDivision of Human Genetics, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA.
Carolyn J PresleyDivision of Medical Oncology, Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA.ORCID 0000-0002-2607-5639
Heather L HampelDivision of Clinical Cancer Genomics, Department of Medical Oncology and Therapeutics Research, City of Hope National Medical Center, Duarte, California, USA.
Tasleem J PadamseeDivision of Health Services Management and Policy, College of Public Health, The Ohio State University, Columbus, Ohio, USA.ORCID 0000-0001-6644-8084
Clara N LeeDivision of Health Services Management and Policy, College of Public Health, The Ohio State University, Columbus, Ohio, USA.
William J IrvinBon Secours Cancer Institute at St. Francis, Richmond, Virginia, USA.
Michael J BishopBon Secours-Mercy Health Lima, Lima, Ohio, USA.
James J KimBon Secours-Mercy Health St. Elizabeth, Youngstown, Ohio, USA.
Shelly R HovickSchool of Communication, Ohio State University, Columbus, Ohio, USA.
Leigha A SenterDivision of Human Genetics, Department of Internal Medicine, The Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA.
Daniel G StoverDivision of Medical Oncology, Ohio State University Comprehensive Cancer Center, Columbus, Ohio, USA.ORCID 0000-0001-9003-8165

Funding

Translational Therapeutics Research Program (TT)P30CA016058 · NCI · OHIO STATE UNIVERSITY · PI Jennifer A. Woyach · 1985 to 2026
$132.3M
Impact of germline variants on racial and ethnic differences in somatic mutation frequencyR01CA215151 · NCI · OHIO STATE UNIVERSITY · PI TOLAND, AMANDA EWART · 2018 to 2022
$1.8M
Resiliency among Older Adults Receiving Lung Cancer Treatment: A Supportive Care Intervention StudyK76AG074923 · NIA · OHIO STATE UNIVERSITY · PI PRESLEY, CAROLYN · 2021 to 2025
$1.2M
Video Intervention to Address Pre-Test Patient Education for Tumor Genomic TestingR21CA259985 · NCI · OHIO STATE UNIVERSITY · PI SENTER-JAMIESON, LEIGHA, STOVER, DANIEL G. · 2021 to 2021
$396k
NCI NIH HHS 1K76AG074923NCI NIH HHS 1R01 CA215151NCI NIH HHS 1R21CA259985NCI NIH HHS P30 CA016058NCI NIH HHS P30CA016058NCI NIH HHS R01 CA215151NCI NIH HHS R21 CA259985NIA NIH HHS K76 AG074923
6 · The paper itself

Abstract

introductionTumor genomic testing (TGT) is standard-of-care for most patients with advanced/metastatic cancer. Despite established guidelines, patient education prior to TGT is frequently omitted. The purpose of this study was to evaluate the impact of a concise 4 min video for patient education prior to TGT.

methodsBased on a quality improvement cycle, an animated video was created to be applicable to any cancer type, incorporating culturally diverse images, available in English and Spanish. Patients undergoing standard-of-care TGT were enrolled at a tertiary academic institution and completed survey instruments prior to video viewing (T1) and immediately post-viewing (T2). Instruments included: (1) 10-question objective genomic knowledge; (2) 10-question video message-specific knowledge; (3) 11-question Trust in Provider; (4) attitudes regarding TGT.

resultsA total of 150 participants were enrolled. For the primary objective, there was a significant increase in video message-specific knowledge (median 10 point increase; p < 0.0001) with no significant change in genomic knowledge/understanding (p = 0.89) or trust in physician/provider (p = 0.59). Results for five questions significantly improved, including the likelihood of TGT impact on treatment decision, incidental germline findings, and cost of testing. Improvement in video message-specific knowledge was consistent across demographic groups, including age, income, and education.

conclusionsA concise, 3-4 min, broadly applicable video incorporating culturally diverse images administered prior to TGT significantly improved video message-specific knowledge across all demographic groups. This resource is publicly available at http://www.tumor-testing.com, with a goal to efficiently educate and empower patients regarding TGT while addressing guidelines within the flow of clinical practice.

Indexed as

Genetic TestingHealth Knowledge, Attitudes, PracticeNeoplasmsPatient Education as TopicVideo RecordingAdultAgedFemaleGenomicsHumansMaleMiddle AgedSurveys and Questionnairesbiomarkerscancer educationcancer managementgenomics

Identifiers

PMID39258462
PMCPMC11387988

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.