ArticleMultiple sclerosis (Houndmills, Basingstoke, England)2024
Brain hemodynamic responses and fall prediction in older adults with multiple sclerosis.
Article in Multiple sclerosis (Houndmills, Basingstoke, England), 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The relationship between motor and cognitive performance and cortical activity in patients with multiple sclerosis: a systematic review of functional near-infrared spectroscopy studies.Frontiers in rehabilitation sciences · 2026Pooled it
- Gait variability predicts falls in older adults with multiple sclerosis.The journals of gerontology. Series A, Biological sciences and medical sciences · 2026Article
- Differential Associations Between Perceived Social Support and Cognition in Older Adults With and Without Multiple Sclerosis.Archives of clinical neuropsychology : the official journal of the National Academy of Neuropsychologists · 2026Article
- Advancing multiple sclerosis management in older adults.Nature reviews. Neurology · 2025Article
- Within-session dual-task walking practice improves gait variability in older adults with multiple sclerosis.Gait & posture · 2025Article
- Brain Connectivity During Walking and Obstacle Avoidance in Persons With Multiple Sclerosis and Healthy Controls: A Pilot EEG Study.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2025Article
- Evaluation of Neural, Systemic and Extracerebral Activations During Active Walking Tasks in Older Adults Using fNIRS.IEEE transactions on neural systems and rehabilitation engineering : a publication of the IEEE Engineering in Medicine and Biology Society · 2025Article
Corrections and comments
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Authors and funding
8 authors.
Funding
Abstract
objectiveWe examined whether brain hemodynamic responses, gait, and cognitive performances under single- and dual-task conditions predict falls during longitudinal follow-up in older adults with multiple sclerosis (OAMS) with relapsing-remitting and progressive subtypes.
methodsParticipants with relapsing-remitting (
resultsAdjusted general estimating equations models indicated that higher HbO under dual-task walking was significantly associated with a reduction in the odds of reporting falls among participants with relapsing-remitting (odds ratio (OR) = 0.472,
conclusionFindings suggest that higher prefrontal cortex activation levels during dual-task walking, which may represent compensatory reallocation of brain resources, provide protection against falls for OAMS with relapsing-remitting subtype.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.