Evidence map›Paper›PMID 39258391›Full record

ArticleRenal failure2024

Plasmapheresis, immunosuppressive therapy and anti-GBM disease prognosis: a cohort study of 107 patients.

Ying Liu, Yiting Wu, Wei Wei, Letian Yang, Caihong Liu, Jian Li, Yongxiu Huang, Bo Wang, Yingying Yang, Ling Zhang and 2 more

Abstract read
In one paragraph

Article in Renal failure, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Anti-glomerular basement membrane disease-treatment standard.Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association · 2025
    Review
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Ying LiuDepartment of Nephrology, West China Hospital, Sichuan University, Chengdu, China.
Yiting WuDepartment of Nephrology, West China Hospital, Sichuan University, Chengdu, China.
Wei WeiDepartment of Nephrology, West China Hospital, Sichuan University, Chengdu, China.
Letian YangDepartment of Nephrology, West China Hospital, Sichuan University, Chengdu, China.
Caihong LiuDepartment of Nephrology, West China Hospital, Sichuan University, Chengdu, China.
Jian LiDepartment of Nephrology, West China Hospital, Sichuan University, Chengdu, China.
Yongxiu HuangDepartment of Nephrology, West China Hospital, Sichuan University, Chengdu, China.
Bo WangDepartment of Nephrology, West China Hospital, Sichuan University, Chengdu, China.
Yingying YangDepartment of Nephrology, West China Hospital, Sichuan University, Chengdu, China.
Ling ZhangDepartment of Nephrology, West China Hospital, Sichuan University, Chengdu, China.
Ping FuDepartment of Nephrology, West China Hospital, Sichuan University, Chengdu, China.
Yuliang ZhaoDepartment of Nephrology, West China Hospital, Sichuan University, Chengdu, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundAnti-glomerular basement membrane (anti-GBM) disease presents with rapidly progressive glomerulonephritis and alveolar hemorrhage, requiring urgent management. In this study, we analyzed the relationship between plasmapheresis strategy, immunosuppressive therapy and the prognosis of anti-GBM disease patients.

methodWe screened newly diagnosed anti-GBM disease patients at West China Hospital of Sichuan University from 2010 to 2021. The primary outcome was a composite endpoint of in-hospital death or dialysis dependency upon discharge.

resultsThis study enrolled 107 anti-GBM disease patients. The use of plasmapheresis was independently associated with a reduced risk of primary outcome (OR: 0.179, 95% Cl: 0.051-0.630,

conclusionPlasmapheresis was protective for both in-hospital outcome and long-term survival in anti-GBM disease. Patients who initiated plasmapheresis early had a better prognosis and might only need 5-10 plasmapheresis sessions to achieve maximal risk reduction. Use of high-dose methylprednisolone or cyclophosphamide pulses was not related to improved short- or long-term outcomes in anti-GBM disease.

Indexed as

Anti-Glomerular Basement Membrane DiseaseImmunosuppressive AgentsPlasmapheresisAdultAgedChinaCohort StudiesFemaleHumansMaleMiddle AgedPrognosisRenal DialysisRetrospective StudiesImmunosuppressive AgentsAnti-GBM diseaseimmunosuppressive therapyplasmapheresisprognosis

Identifiers

PMID39258391
PMCPMC11391867

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.