Evidence map›Paper›PMID 39258295›Full record

ArticleFrontiers in plant science2024

Parallel evolution of methyltransferases leads to vobasine biosynthesis in

Maisha Farzana, Matthew Bailey Richardson, Daniel André Ramey Deschênes, Zhan Mai, Destiny Ichechi Njoku, Ghislain Deslongchamps, Yang Qu

Abstract read
In one paragraph

Article in Frontiers in plant science, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Maisha FarzanaDepartment of Chemistry, University of New Brunswick, Fredericton, NB, Canada.
Matthew Bailey RichardsonDepartment of Chemistry, University of New Brunswick, Fredericton, NB, Canada.
Daniel André Ramey DeschênesDepartment of Chemistry, University of New Brunswick, Fredericton, NB, Canada.
Zhan MaiDepartment of Chemistry, University of New Brunswick, Fredericton, NB, Canada.
Destiny Ichechi NjokuDepartment of Chemistry, University of New Brunswick, Fredericton, NB, Canada.
Ghislain DeslongchampsDepartment of Chemistry, University of New Brunswick, Fredericton, NB, Canada.
Yang QuDepartment of Chemistry, University of New Brunswick, Fredericton, NB, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Monoterpenoid indole alkaloids (MIA) are one of the largest and most complex alkaloid class in nature, boasting many clinically significant drugs such as anticancer vinblastine and antiarrhythmic ajmaline. Many MIAs undergo nitrogen

Indexed as

methyltransferasemonoterpenoid indole alkaloidnatural product biosynthesisparallel evolutionTabernaemontana elegansvobasine

Identifiers

PMID39258295
PMCPMC11383786

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.