ArticleFrontiers in pediatrics2024
Predictors of CPAP failure after less-invasive surfactant administration in preterm infants.
Article in Frontiers in pediatrics, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Safety of Less Invasive Surfactant Administration in Preterm Infants: A Meta-Analysis.Pediatric pulmonology · 2026Pooled it
- Comparison of nasal interfaces and pressures during critical time-points in NICU: observation data from over 10 years.Journal of perinatology : official journal of the California Perinatal Association · 2026Article
- Minimally invasive surfactant administration in extremely preterm infants <28 weeks gestation with spontaneous breathing: a retrospective quality improvement study on reducing invasive ventilation burden.Frontiers in pediatrics · 2026Article
- Impact of LISA failure on 2-year neurodevelopmental outcomes in preterm infants: a retrospective cohort study.BMJ paediatrics open · 2025Article
- Factors Associated with Intubation After Less Invasive Surfactant Administration (LISA); A Single-Center Cohort from Saudi Arabia.Children (Basel, Switzerland) · 2025Article
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Authors and funding
12 authors.
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Abstract
Introduction: Less-invasive surfactant administration (LISA) is associated with better respiratory outcomes in preterm infants with respiratory distress syndrome. However, mechanical ventilation (MV) shortly after the LISA procedure has been related to lower survival. This study aimed to analyze the trends and main predictors of continuous positive airway pressure (CPAP) failure after LISA. Material and methods: Preterm infants born between 23 Results: Over the study period, 289 inborn preterm infants received surfactant, 174 with the LISA method (60.2%). Patients who received surfactant after intubation in the delivery room ( Conclusions: CPAP failure after LISA is still common in extremely preterm infants, leading to an increase in death or disability. Clinicians must acknowledge the main risk factors of CPAP failure to choose wisely the right patient and the best technique. LUS and the SF ratio at admission can be useful when making these decisions.
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