ReviewPreventive medicine reports2024
The effects of physical inactivity on other risk factors for chronic disease: A systematic review of reviews.
Review in Preventive medicine reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06749249 (Enjoyment Mediates Long-term Changes in Physical Activity Level in a Physical Activity on Prescription Intervention), which is not on this map. Cited by 9 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Enjoyment Mediates Long-term Changes in Physical Activity Level in a Physical Activity on Prescription Intervention
Who cites it
9 citing papers in PubMed.
- Trial
- Eating Behavior and Physical Activity Changes Among Adult Mexican Women After the COVID-19 Pandemic.American journal of lifestyle medicine · 2026Article
- Review
- Physical Activity Prevalence and Sex-Associated Factors Among University Students During the First Year of the COVID-19 Pandemic: A Cross-Sectional Study.Sports (Basel, Switzerland) · 2026Article
- Table Tennis for Health and Wellbeing: A Rapid Scoping Review.Sports (Basel, Switzerland) · 2026Review
- Assessing the Impact of Sharrows on Bicyclist Behavior: A three-year natural experiment in Santa Ana, California.Journal of healthy eating and active living · 2026Article
- Multifactorial determinants of cardiovascular disease: The role of socio-demographic, lifestyle, and morbidity factors.Journal of education and health promotion · 2026Article
- Five Years Later-The Impact of the COVID-19 Pandemic on Physical Performance and Cardiometabolic Health Using a Smart Home Gym: An Ecological Case Study.International journal of environmental research and public health · 2025Article
- Knee and hip osteoarthritis increase the risk of cardiovascular disease: A national registry-based longitudinal cohort study.PloS one · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: The Global Burden of Disease (GBD) 2021 study updated methods for attributing burden to physical inactivity, to include all conditions from fasting plasma glucose (FPG) due to physical inactivity. However, physical inactivity influences several additional GBD risk factors that also effect other diseases. This study estimated effects of physical activity on high blood pressure (hypertension), FPG (as diabetes), osteoporosis, and LDL-cholesterol, to enable mediation effects modelling. Methods: MEDLINE, ProQuest Central, Scopus, EMBASE, SPORTDiscus, and Cochrane Library databases were searched from inception to 29 June 2024 for systematic reviews reporting total physical activity levels as an exposure and at least one of the above GBD risk factors or BMI as outcomes. Results: There were 25 systematic reviews that met the inclusion criteria (3 for hypertension, 5 for diabetes, 1 for osteoporosis, and 16 for LDL-cholesterol). Physical activity reduced levels of the risk factors investigated, with dose-response effects observed for blood pressure (6 % for every 600 MET-min/week; 19 % for high versus low activity level) and diabetes (14-28 % if active versus being inactive). Relative to adults not reporting any activity, approximately 600 METs/week reduced levels of LDL-cholesterol by 3.2 % (95 % CI: 1.0 % to 5.4 %) and reduced low bone mineral density by an odds ratio of 0.76 (0.64 to 0.91). No studies of high BMI were identified. Conclusion: Current risk factor models do not comprehensively assess indirect effects of physical activity through all of the relevant biomedical risk factors. Our study estimated input parameters that can be used to assess these indirect pathways.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.