Evidence map›Paper›PMID 39257810›Full record

ArticlebioRxiv : the preprint server for biology2024

Centromeric transposable elements and epigenetic status drive karyotypic variation in the eastern hoolock gibbon.

Gabrielle A Hartley, Mariam Okhovat, Savannah J Hoyt, Emily Fuller, Nicole Pauloski, Nicolas Alexandre, Ivan Alexandrov, Ryan Drennan, Danilo Dubocanin, David M Gilbert and 13 more

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

23 authors.

Gabrielle A HartleyInstitute for Systems Genomics, University of Connecticut, Storrs, CT, USA.ORCID 0000-0002-5672-2171
Mariam OkhovatDepartment of Medicine, Knight Cardiovascular Institute, Oregon Health and Science University, Portland, OR, USA.
Savannah J HoytInstitute for Systems Genomics, University of Connecticut, Storrs, CT, USA.ORCID 0000-0001-7804-3236
Emily FullerInstitute for Systems Genomics, University of Connecticut, Storrs, CT, USA.
Nicole PauloskiInstitute for Systems Genomics, University of Connecticut, Storrs, CT, USA.ORCID 0009-0004-6135-7078
Nicolas AlexandreDepartment of Ecology and Evolutionary Biology, University of California, Santa Cruz, CA, USA.ORCID 0000-0003-1530-1570
Ivan AlexandrovDepartment of Anatomy and Anthropology and Department of Human Molecular Genetics and Biochemistry, Faculty of Medicine, Tel Aviv University, Israel.ORCID 0000-0003-4342-2003
Ryan DrennanInstitute for Systems Genomics, University of Connecticut, Storrs, CT, USA.ORCID 0009-0003-9918-1621
Danilo DubocaninDivision of Medical Genetics, Department of Medicine, University of Washington, Seattle, WA, USA.
David M GilbertSan Diego Biomedical Research Institute, San Diego, CA 92121, USA.ORCID 0000-0001-8087-9737
Yizi MaoDivision of Medical Genetics, Department of Medicine, University of Washington, Seattle, WA, USA.ORCID 0000-0001-5743-6831
Christine McCannInstitute for Systems Genomics, University of Connecticut, Storrs, CT, USA.ORCID 0009-0003-6256-4864
Shane NephDivision of Medical Genetics, Department of Medicine, University of Washington, Seattle, WA, USA.
Fedor RyabovUC Santa Cruz Genomics Institute, University of California Santa Cruz, Santa Cruz, CA, USA.ORCID 0000-0001-8728-9465
Takayo SasakiSan Diego Biomedical Research Institute, San Diego, CA 92121, USA.ORCID 0000-0001-7609-9316
Jessica M StorerInstitute for Systems Genomics, University of Connecticut, Storrs, CT, USA.
Derek SvendsenInstitute for Systems Genomics, University of Connecticut, Storrs, CT, USA.
William TroyFormBio, Dallas, TX, USA.ORCID 0000-0002-7906-0887
Jackson WellsDepartment of Medicine, Knight Cardiovascular Institute, Oregon Health and Science University, Portland, OR, USA.ORCID 0000-0002-4542-8604
Leighton CoreInstitute for Systems Genomics, University of Connecticut, Storrs, CT, USA.ORCID 0000-0002-1698-1144
Andrew StergachisDivision of Medical Genetics, Department of Medicine, University of Washington, Seattle, WA, USA.ORCID 0000-0002-1299-3674
Lucia CarboneDepartment of Medicine, Knight Cardiovascular Institute, Oregon Health and Science University, Portland, OR, USA.
Rachel J O'NeillInstitute for Systems Genomics, University of Connecticut, Storrs, CT, USA.ORCID 0000-0002-1525-6821

Funding

Upgrade of confocal microscopy at the Oregon National Primate Research CenterP51OD011092 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI Bonnie J. Nagel · 2012 to 2026
$203.9M
Computational Methods for Next-Generation Comparative GenomicsR01HG007352 · NHGRI · UNIVERSITY OF ILLINOIS AT URBANA-CHAMPAIGN · PI MA, JIAN · 2014 to 2023
$2.8M
Comparative and functional analysis of conservation and rearrangement of topologically associating domains across mammals.R01HG010333 · NHGRI · OREGON HEALTH & SCIENCE UNIVERSITY · PI CARBONE, LUCIA · 2018 to 2021
$2.8M
The Role of Retroelements in Centromere FunctionR01GM123312 · NIGMS · UNIVERSITY OF CONNECTICUT STORRS · PI O'NEILL, RACHEL · 2019 to 2022
$1.9M
NHGRI NIH HHS R01 HG007352NHGRI NIH HHS R01 HG010333NIGMS NIH HHS R01 GM123312NIH HHS P51 OD011092
6 · The paper itself

Abstract

Great apes have maintained a stable karyotype with few large-scale rearrangements; in contrast, gibbons have undergone a high rate of chromosomal rearrangements coincident with rapid centromere turnover. Here we characterize assembled centromeres in the Eastern hoolock gibbon,

Indexed as

centromereschromosome evolutiongenome assemblygibbonsmethylationprimate genomicsreplication timingtransposable elements

Identifiers

PMID39257810
PMCPMC11384015

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.