Evidence map›Paper›PMID 39257796›Full record

ArticlebioRxiv : the preprint server for biology2024

Negative feedback of cyclic di-GMP levels optimizes switching between sessile and motile lifestyles in

Aathmaja Anandhi Rangarajan, Jeremy W Schroeder, Rebecca L Hurto, Geoffrey B Severin, Macy E Pell, Meng-Lun Hsieh, Christopher M Waters, Lydia Freddolino

Abstract readPreprint
PubMed Full text at PMC Publisher
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Aathmaja Anandhi RangarajanDepartment of Microbiology, Genetics and Immunology, Michigan State University, East Lansing, MI, USA.ORCID 0000-0003-3471-0257
Jeremy W SchroederDepartment of Biological Chemistry, University of Michigan, Ann Arbor, MI 48109, USA.ORCID 0000-0001-8829-8494
Rebecca L HurtoDepartment of Biological Chemistry, University of Michigan, Ann Arbor, MI 48109, USA.
Geoffrey B SeverinDepartment of Microbiology and Immunology, University of Michigan, Ann Arbor, MI, USA.ORCID 0000-0003-2441-5916
Macy E PellDepartment of Microbiology, Genetics and Immunology, Michigan State University, East Lansing, MI, USA.ORCID 0000-0002-1846-5063
Meng-Lun HsiehDepartment of Microbiology, Genetics and Immunology, Michigan State University, East Lansing, MI, USA.ORCID 0000-0002-6360-005X
Christopher M WatersDepartment of Microbiology, Genetics and Immunology, Michigan State University, East Lansing, MI, USA.ORCID 0000-0003-2336-7836
Lydia FreddolinoDepartment of Biological Chemistry, University of Michigan, Ann Arbor, MI 48109, USA.ORCID 0000-0002-5821-4226

Funding

Building a unified framework for understanding bacterial gene regulation and chromosomal architectureR35GM128637 · NIGMS · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Lydia Petra Freddolino · 2018 to 2026
$3.6M
Exploring cyclic di-nucleotide signaling across the tree of life (Supplement)R35GM139537 · NIGMS · MICHIGAN STATE UNIVERSITY · PI WATERS, CHRISTOPHER M · 2021 to 2025
$2.9M
The contribution of novel cytidine deaminase regulatory systems to bacterial evolutionR01AI158433 · NIAID · MICHIGAN STATE UNIVERSITY · PI NEIDITCH, MATTHEW B, WATERS, CHRISTOPHER M · 2021 to 2025
$2.9M
NIAID NIH HHS R01 AI158433NIGMS NIH HHS R35 GM128637NIGMS NIH HHS R35 GM139537
6 · The paper itself

Abstract

The signaling molecule cyclic di-GMP (cdG) controls the switch between bacterial motility and biofilm production, and fluctuations in cellular levels of cdG have been implicated in

Identifiers

PMID39257796
PMCPMC11383701

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.