Evidence map›Paper›PMID 39257776›Full record

ArticlebioRxiv : the preprint server for biology2024

O-glycosylation contributes to mammalian glycoRNA biogenesis.

Jennifer Porat, Christopher P Watkins, Chunsheng Jin, Xixuan Xie, Xiao Tan, Charlotta G Lebedenko, Helena Hemberger, Woojung Shin, Peiyuan Chai, James J Collins and 3 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Jennifer PoratStem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Boston, USA.ORCID 0000-0002-1709-4635
Christopher P WatkinsStem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Boston, USA.ORCID 0009-0000-5045-5001
Chunsheng JinProteomics Core Facility at Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
Xixuan XieState Key Laboratory of Genetic Engineering, Greater Bay Area Institute of Precision Medicine (Guangzhou), School of Life Sciences and Institutes of Biomedical Sciences, Fudan University, Shanghai 200438, China.ORCID 0000-0002-8512-6053
Xiao TanWyss Institute of Biologically Inspired Engineering, Harvard University, Boston, USA.
Charlotta G LebedenkoStem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Boston, USA.ORCID 0000-0002-9891-9247
Helena HembergerStem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Boston, USA.ORCID 0009-0007-4535-5859
Woojung ShinWyss Institute of Biologically Inspired Engineering, Harvard University, Boston, USA.ORCID 0000-0002-1780-0317
Peiyuan ChaiStem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Boston, USA.ORCID 0000-0002-9203-8975
James J CollinsWyss Institute of Biologically Inspired Engineering, Harvard University, Boston, USA.
Benjamin A GarciaDepartment of Biochemistry and Molecular Biophysics, Washington University School of Medicine, St. Louis, MO, USA.
Daniel BojarDepartment of Chemistry and Molecular Biology, University of Gothenburg, Gothenburg, Sweden. Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Gothenburg, Sweden.ORCID 0000-0002-3008-7851
Ryan A FlynnStem Cell Program and Division of Hematology/Oncology, Boston Children's Hospital, Boston, USA.ORCID 0000-0001-5013-0442

Funding

Mechanisms and functions of cell surface glycoRNAsR35GM151157 · NIGMS · BOSTON CHILDREN'S HOSPITAL · PI Ryan Alexander Flynn · 2023 to 2026
$1.8M
Machine learning-based methods for the analysis of microbial glycomes and proteomes in inflammatory bowel disease.K08DK132516 · NIDDK · MASSACHUSETTS GENERAL HOSPITAL · PI Xiao Tan · 2023 to 2026
$678k
NIDDK NIH HHS K08 DK132516NIGMS NIH HHS R35 GM151157
6 · The paper itself

Abstract

There is an increasing appreciation for the role of cell surface glycans in modulating interactions with extracellular ligands and participating in intercellular communication. We recently reported the existence of sialoglycoRNAs, where mammalian small RNAs are covalently linked to N-glycans through the modified base acp

Identifiers

PMID39257776
PMCPMC11384000

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.