Evidence map›Paper›PMID 39257737›Full record

ArticlebioRxiv : the preprint server for biology2024

Brain Charts for the Rhesus Macaque Lifespan.

S Alldritt, J S B Ramirez, R Vos de Wael, R Bethlehem, J Seidlitz, Z Wang, K Nenning, N B Esper, J Smallwood, A R Franco and 112 more

Abstract readPreprint
In one paragraph

Article in bioRxiv : the preprint server for biology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

122 authors.

S AlldrittCenter for the Integrative Developmental Neuroscience, Child Mind Institute.
J S B RamirezChild Mind Institute.
R Vos de WaelChild Mind Institute.
R BethlehemUniversity of Cambridge, Department of Psychology.
J SeidlitzUniversity of Pennsylvania.
Z WangChild Mind Institute.
K NenningNathan Kline Institute.
N B EsperChild Mind Institute.
J SmallwoodQueens University.
A R FrancoChild Mind Institute.
K ByeonChild Mind Institute.
A Alexander-BlochDepartment of Child and Adolescent Psychiatry and Behavioral Science, Children's Hospital of Philadelphia.
D G AmaralDepartment of Psychiatry and Behavioral Sciences and The MIND Institute.
C AmiezStem Cell and Brain Research Institute.
F BalezeauNewcastle University.
M G BaxterSection on Comparative Medicine, Wake Forest University School of Medicine.
G BeckerUniversite Claude Bernard Lyon 1.
J BennettUniversity of California Davis, Dept of Psychology.
O BerknerTranslational Neuroscience division, Center for Biomedical Imaging and Neuromodulation, Nathan Kline Institute.
E L A BlezerUniversity Medical Center Utrecht.
A M BrambrinkColumbia University.
T BrochierAix-Marseille University.
B ButlerTranslational Neuroscience Division, Center for Biomedical Imaging and Neuromodulation, Nathan Kline Institute.
L J CamposUniversity of California Davis.
E Canet-SoulasUniversite Claude Bernard Lyon 1.
L ChaletUniversite Claude Bernard Lyon1.
A ChenEast China Normal University.
J CléryMcGill University.
C ConstantinidisDepartment of Biomedical Engineering, Vanderbilt University.
D J CookQueens University.
S DehaeneNeuroSpin.
L DorfschmidtUniversity of Pennsylvania.
C M DrzewieckiUniversity of California Davis.
J W ErdmanUniversity of Illinois Urbana-Champaign.
S EverlingUniversity of Western Ontario.
A FalchierTranslational Neuroscience Division, Center for Biomedical Imaging and Neuromodulation, Nathan Kline Institute.
L FleysherMount Sinai School of Medicine.
A FoxUniversity of California Davis.
W FreiwaldRockefeller University.
M FroeselInstitute for Cognitive Science Marc Jeannerod.
S Froudist-WalshUniversity of Bristol.
J FudgeUniversity of Rochester.
T FunckChild Mind Institute.
M GacoinInstitute for Cognitive Science Marc Jeannerod.
D J GaleQueen's University.
J GallivanQueens University.
C M GarinInstitut des Sciences Cognitives Marc Jeannerod (ISC-MJ).
T D GriffithsNewcastle University.
C GuedjLyon Neuroscience Research Center, University of Geneva.
F Hadj-BouzianeLyon Neuroscience Research Center, ImpAct Team.
S B HamedInstitute for Cognitive Science Marc Jeannerod.
N HarelUniversity of Minnesota.
R HartigTranslational Neuroscience division, Center for Biomedical Imaging and Neuromodulation, Nathan Kline Institute.
B HibaInstitute for Cognitive Science Marc Jeannerod.
B R HowellEmory National Primate Research Center, Emory University.
B JarrayaNeuroSpin.
B JungUniversity of Pennsylvania.
N KalinUniversity of Wisconsin Madison.
J KarpfOregon National Primate Research Center.
S KastnerPrinceton Neuroscience Institute & Department of Psychology, Princeton University.
C KlinkNetherlands Institute for Neuroscience.
Z A Kovacs-BalintEmory National Primate Research Center; Emory University.
C KroenkeOregon National Primate Research Center.
M J KuchanAbbott Laboratories.
S C KwokDuke Kunshan University.
K N LalaCentre for Social Learning and Cognitive Evolution, School of Biology, University of St. Andrews.
D A LeopoldNational Institute of Mental Health.
G LiUniversity of North Carolina at Chapel Hill.
P LindenforsInstitute for Futures Studies, Stockholm, Sweden.
G LinnTranslational Neuroscience division, Center for Biomedical Imaging and Neuromodulation, Nathan Kline Institute.
R B MarsUniversity of Oxford.
K MasielloTranslational Neuroscience division, Center for Biomedical Imaging and Neuromodulation, Nathan Kline Institute.
R S MenonThe University of Western Ontario.
A MessingerNational Institute of Mental Health.
M MeunierLyon Neuroscience Research Center, ImpAct Team.
K MokMcGill University.
J H MorrisonCalifornia National Primate Research Center, Davis.
J NacefNewcastle University.
J NagyDepartment of Neuroscience, Icahn School of Medicine at Mount Sinai.
V NeudeckerColumbia University.
M NeuringerOregon Health & Science University.
M P NoonanUniversity of York.
M Ortiz-RiosFunctional Imaging Laboratory, German Primate Center - Leibniz Institute for Primate Research.
J F Perez-ZoghbiColumbia University.
C I PetkovNewcastle University, University of Iowa.
M PinskPrinceton Neuroscience Institute, Princeton University.
C PoirierNewcastle University.
E ProcykStem Cell and Brain Research Institute.
R RajimehrMcGovern Institute for Brain Research, Massachusetts Institute of Technology.
S M ReaderDepartment of Biology, Utrecht University.
D A RudkoMcGill University.
M F S RushworthUniversity of Oxford.
B E RussTranslational Neuroscience division, Center for Biomedical Imaging and Neuromodulation, Nathan Kline Institute.
J SalletINSERM Stem Cell & Brain Research Institute.
M M SanchezDepartment of Psychiatry & Behavioral Sciences, School of Medicine.
M C SchmidUniversity of Fribourg, Switzerland.
C M SchwiedrzikRuhr University Bochum, Faculty of Biology and Biotechnology, Cognitive Neurobiology.
J A ScottDepartment of Bioengineering, Santa Clara University.
J SeinAix-Marseille University.
K K SharmaUniversity of Rochester.
A ShmuelMcGill University.
M StynerUniversity of North Carolina at Chapel Hill.
E L SullivanOregon Health & Science University.
A ThieleNewcastle University.
O S TodorovDepartment of Biology and Helmholtz Institute, Utrecht University.
D TsaoDepartment of Computation and Neural Systems, California Institute of Technology.
A TuscheQueens University.
R VlasovaUniversity of North Carolina at Chapel Hill.
Z WangInstitute of Neuroscience.
L WangEast China Normal University.
J WangState Key Laboratory of Primate Biomedical Research, Institute of Primate Translational Medicine, Kunming University of Science and Technology, Kunming, China.
A R WeissOregon National Primate Research Center.
C R E WilsonStem Cell & Brain Research Institute.
E YacoubUniversity of Minnesota.
W ZarcoThe Rockefeller University.
Y ZhouKrieger Mind/Brain Institute, Department of Neurosurgery, Johns Hopkins University.
J ZhuDepartment of Biomedical Engineering, Vanderbilt University.
D MarguliesFrench National Centre for Scientific Research.
D FairUniversity of Minnesota.
C SchroederTranslational Neuroscience division, Center for Biomedical Imaging and Neuromodulation, Nathan Kline Institute.
M MilhamChild Mind Institute.
T XuCenter for the Integrative Developmental Neuroscience, Child Mind Institute.ORCID 0000-0002-0065-3832

Funding

Upgrade of confocal microscopy at the Oregon National Primate Research CenterP51OD011092 · OD · OREGON HEALTH & SCIENCE UNIVERSITY · PI Bonnie J. Nagel · 2012 to 2026
$203.9M
National Institute on Aging (NIA) ColonyP51OD011107 · OD · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Simon J. Atkinson · 2012 to 2026
$191.5M
Yerkes National Primate Research Center Role of type-I IFN in regulating COVID-19 induced inflammation and pathogenesisP51OD011132 · OD · EMORY UNIVERSITY · PI Joon Sup Lee · 2012 to 2026
$167.0M
Project 5: ComputationalP50MH109429 · NIMH · NATHAN S. KLINE INSTITUTE FOR PSYCH RES · PI STEPHANIE Ruggiano JONES · 2017 to 2026
$25.3M
NEUROSCIENCE TRAINING IN DRUG ABUSE RESEARCHT32DA007234 · NIDA · UNIVERSITY OF MINNESOTA TWIN CITIES · PI Paul G Mermelstein, Jocelyn M Richard · 1986 to 2026
$10.9M
Defining Neuronal Circuits and Cellular Processes Underlying Resting fMRI SignalsR01MH111439 · NIMH · NATHAN S. KLINE INSTITUTE FOR PSYCH RES · PI MILHAM, MICHAEL PETER, SCHROEDER, CHARLES E · 2016 to 2020
$5.1M
The Genetics of Personalized Functional MRI NetworksR01MH132934 · NIMH · CHILDREN'S HOSP OF PHILADELPHIA · PI Aaron Felix Alexander-Bloch · 2023 to 2026
$4.2M
The NKI Rockland Sample II: An Open Resource of Multimodal Brain, Physiology & Behavior Data from a Community Lifespan SampleR01MH124045 · NIMH · NATHAN S. KLINE INSTITUTE FOR PSYCH RES · PI COLCOMBE, STAN J, MILHAM, MICHAEL PETER · 2021 to 2025
$3.7M
Precision brain charts for imaging-genomics of schizophrenia and the psychosis spectrumR01MH133843 · NIMH · CHILDREN'S HOSP OF PHILADELPHIA · PI Aaron Felix Alexander-Bloch · 2023 to 2026
$3.2M
Resolving amygdala microcircuits: implications for functionR01MH130608 · NIMH · UNIVERSITY OF ROCHESTER · PI JULIE L. FUDGE · 2022 to 2026
$2.6M
Radiomics for Clinically-Acquired Brain MRIs of Youth with Neurodevelopmental DisordersR01MH134896 · NIMH · CHILDREN'S HOSP OF PHILADELPHIA · PI Aaron Felix Alexander-Bloch · 2024 to 2026
$2.3M
Laminar Circuit Motifs for Working Memory and Language Combinatorics: From Cells to SystemsU01NS137991 · NINDS · UNIVERSITY OF IOWA · PI Jeremy Greenlee, Christopher I Petkov · 2024 to 2026
$2.3M
NIDA NIH HHS T32 DA007234NIH HHS P51 OD011092NIH HHS P51 OD011107NIH HHS P51 OD011132NIMH NIH HHS P50 MH109429NIMH NIH HHS R01 MH111439NIMH NIH HHS R01 MH124045NIMH NIH HHS R01 MH130608NIMH NIH HHS R01 MH132934NIMH NIH HHS R01 MH133843NIMH NIH HHS R01 MH134896NIMH NIH HHS R01 MH139565NIMH NIH HHS RF1 MH128696NINDS NIH HHS U01 NS137991
6 · The paper itself

Abstract

Recent efforts to chart human brain growth across the lifespan using large-scale MRI data have provided reference standards for human brain development. However, similar models for nonhuman primate (NHP) growth are lacking. The rhesus macaque, a widely used NHP in translational neuroscience due to its similarities in brain anatomy, phylogenetics, cognitive, and social behaviors to humans, serves as an ideal NHP model. This study aimed to create normative growth charts for brain structure across the macaque lifespan, enhancing our understanding of neurodevelopment and aging, and facilitating cross-species translational research. Leveraging data from the PRIMatE Data Exchange (PRIME-DE) and other sources, we aggregated 1,522 MRI scans from 1,024 rhesus macaques. We mapped non-linear developmental trajectories for global and regional brain structural changes in volume, cortical thickness, and surface area over the lifespan. Our findings provided normative charts with centile scores for macaque brain structures and revealed key developmental milestones from prenatal stages to aging, highlighting both species-specific and comparable brain maturation patterns between macaques and humans. The charts offer a valuable resource for future NHP studies, particularly those with small sample sizes. Furthermore, the interactive open resource (https://interspeciesmap.childmind.org) supports cross-species comparisons to advance translational neuroscience research.

Identifiers

PMID39257737
PMCPMC11383706

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.