Evidence map›Paper›PMID 39257475›Full record

ArticleUpsala journal of medical sciences2024

Personality vulnerability to depression, resilience, and depressive symptoms: epigenetic markers among perinatal women.

Rita T Amiel Castro, Elena Gardini, Stavros I Iliadis, Ulrike Ehlert, Theodora Kunovac Kallak, Alkistis Skalkidou

Abstract read
In one paragraph

Article in Upsala journal of medical sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Biomarkers of reproductive psychiatric disorders.The British journal of psychiatry : the journal of mental science · 2025
    Review
  6. Article
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Rita T Amiel CastroDepartment of Clinical Psychology and Psychotherapy, University of Zurich, Institute of Psychology, Zurich, Switzerland.
Elena GardiniDepartment of Clinical Psychology and Psychotherapy, University of Zurich, Institute of Psychology, Zurich, Switzerland.
Stavros I IliadisDepartment of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Ulrike EhlertDepartment of Clinical Psychology and Psychotherapy, University of Zurich, Institute of Psychology, Zurich, Switzerland.
Theodora Kunovac Kallak *Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.
Alkistis Skalkidou *Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: We examined differences in DNA methylation patterns in the Methods: Results: Conclusions: This study identified associations between NR3C1 methylation and resilience as well as perinatal depressive symptoms. Interestingly, an interaction between early trauma and personality vulnerability was noted. Our findings on these specific DNA methylation markers may, if replicated and integrated into risk prediction models, contribute to early diagnosis of mothers at risk, targeted health promotion, and early interventions.

Indexed as

DepressionDNA MethylationEpigenesis, GeneticReceptors, GlucocorticoidResilience, PsychologicalTacrolimus Binding ProteinsAdultBiomarkersCpG IslandsDepression, PostpartumFemaleHumansPersonalityPregnancySurveys and QuestionnairesTacrolimus Binding Protein 5BiomarkersNR3C1 protein, humanReceptors, GlucocorticoidTacrolimus Binding Protein 5Tacrolimus Binding Proteinsdepressive symptomsepigeneticspregnancyresilienceTrauma

Identifiers

PMID39257475
PMCPMC11385460

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.