Evidence map›Paper›PMID 39256683›Full record

Observational studyBMC nephrology2024

Estimates of eskd risk and timely kidney replacement therapy education.

Lauren E Haggerty, Dena E Rifkin, Hoang Anh Nguyen, Joseph A Abdelmalek, Natalie Sweiss, Lindsay M Miller, O Alison Potok

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in BMC nephrology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Lauren E HaggertyDivision of Nephrology-Hypertension, University of Washington, Seattle, WA, USA.
Dena E RifkinDivision of Nephrology-Hypertension, University of California, San Diego, CA, USA.
Hoang Anh NguyenDivision of Nephrology-Hypertension, University of California, Irvine, CA, USA.
Joseph A AbdelmalekDivision of Nephrology-Hypertension, University of California, San Diego, CA, USA.
Natalie SweissDivision of Nephrology-Hypertension, University of California, San Diego, CA, USA.
Lindsay M MillerDivision of Nephrology-Hypertension, University of California, San Diego, CA, USA.
O Alison PotokDivision of Nephrology-Hypertension, University of California, San Diego, CA, USA. opotok@health.ucsd.edu.

Funding

The Clinical Applications of the Difference in Estimated Glomerular Filtration Rate by Cystatin C vs. Creatinine (eGFRDiff)K23DK128604 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI POTOK, OLIVIA ALISON · 2021 to 2025
$951k
Beyond the Glomerulus: Kidney Tubule Dysfunction and Cognitive Impairments in the ElderlyF32DK127590 · NIDDK · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI MILLER, LINDSAY M. · 2020 to 2021
$135k
NIDDK NIH HHS K23 DK128604NIH HHS F32DK127590NIH HHS K23DK128604U.S. Department of Veterans Affairs H160180
6 · The paper itself

Abstract

backgroundKidney replacement therapy (KRT) needs preparation and its timing is difficult to predict. Nephrologists' predictions of kidney failure risk tend to be more pessimistic than the Kidney Failure Risk Equation (KFRE) predictions. We aimed to explore how physicians' risk estimate related to referral to KRT education, vs. the objective calculated KFRE.

methodsProspective observational study of data collected in chronic kidney disease (CKD) clinics of the Veterans Affairs Medical Center San Diego and the University of California, San Diego. The study included 257 participants who were aged 18 years or older, English speaking, prevalent CKD clinic patients, with estimated glomerular filtration rate (eGFR) < 60 mL/min per 1.73 m

resultsA fifth were referred for education by 90 days of enrollment. Low risk patients by both estimates had low referral rates. In those with nephrologists' predictions ≥ 15% (n = 137), sensitivity was 71% and specificity 76%. In those with KFRE ≥ 15% (n = 55), sensitivity was 85% and specificity 41%.

conclusionsAlthough nephrologists tend to overestimate patients' kidney failure risk, they do not appear to act on this overestimation, as the rates of KRT education referrals are lower than expected when a nephrologist identifies a patient as high risk. CLINICAL TRIAL NUMBER: Not applicable.

Indexed as

Kidney Failure, ChronicRenal Replacement TherapyAdultAgedFemaleGlomerular Filtration RateHumansMaleMiddle AgedPatient Education as TopicProspective StudiesReferral and ConsultationRisk AssessmentCKDDialysis preparationEducationESKD riskKFREKidney failureKidney replacement therapy

Identifiers

PMID39256683
PMCPMC11384691

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.