Evidence map›Paper›PMID 39256424›Full record

ArticleScientific reports2024

Long-term brain structural and cognitive outcomes in a low-risk preterm-born sample.

L Fernández de Gamarra-Oca, Natalia Ojeda, J M Ontañón, B Loureiro-Gonzalez, A Gómez-Gastiasoro, J Peña, N Ibarretxe-Bilbao, M A García-Guerrero, L Zubiaurre-Elorza

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

L Fernández de Gamarra-OcaDepartment of Psychology, Faculty of Health Sciences, University of Deusto, Avda de las Universidades 24, 48007, Bilbao, Bizkaia, Spain. Lexuri.fernandez@deusto.es.
Natalia OjedaDepartment of Psychology, Faculty of Health Sciences, University of Deusto, Avda de las Universidades 24, 48007, Bilbao, Bizkaia, Spain. nojeda@deusto.es.ORCID 0000-0002-0952-0649
J M OntañónOSATEK, MR Unit, Hospital of Galdakao, Galdakao, Bizkaia, Spain.
B Loureiro-GonzalezDivision of Neonatology, Biocruces Health Research Institute, Cruces University Hospital, Barakaldo, Bizkaia, Spain.
A Gómez-GastiasoroDepartment of Basic Psychological Processes and Development, Faculty of Psychology, University of the Basque Country, Donostia, Gipuzkoa, Spain.
J PeñaDepartment of Psychology, Faculty of Health Sciences, University of Deusto, Avda de las Universidades 24, 48007, Bilbao, Bizkaia, Spain.
N Ibarretxe-BilbaoDepartment of Psychology, Faculty of Health Sciences, University of Deusto, Avda de las Universidades 24, 48007, Bilbao, Bizkaia, Spain.
M A García-GuerreroDepartment of Psychology, Faculty of Health Sciences, University of Deusto, Avda de las Universidades 24, 48007, Bilbao, Bizkaia, Spain.
L Zubiaurre-ElorzaDepartment of Psychology, Faculty of Health Sciences, University of Deusto, Avda de las Universidades 24, 48007, Bilbao, Bizkaia, Spain.

Funding

Aristos Campus Mundus ACM2018_17Department of Education and Science of the Basque Government IT1545-22Department of Education of the Basque Government PRE_2019_1_0105Spanish Ministry of Science, Innovation and Universities PSI2017-83657-P
6 · The paper itself

Abstract

Prematurity has been related to altered brain structure and cognition, and so our aim was to describe them in the absence of major structural brain injury following low-risk preterm birth during adolescence and young adulthood. The sample consisted of 250 participants, 132 of whom were low-risk preterm (30-36 weeks' gestational age) and 118 were full-term individuals (37-42 weeks' gestational age), aged between 16 and 38 years old. All participants underwent an extensive neuropsychological assessment. T1- and diffusion-weighted MRI images of 33 low-risk preterm and 31 full-term young adults (20-32 years old) were analyzed. No differences were found in terms of general cognitive functioning score or current socioeconomic status; however, the low-risk preterm group obtained lower scores in phonetic and semantic fluencies, and theory of mind. Significant reductions were identified in the thalamus volume as well as thicker cortex in the inferior temporal gyrus in the low-risk preterm group. Low-risk preterm young adults evidenced greater regional AD and MD compared to the full-term sample; while low-risk preterm group showed lower mean NDI and ODI (FWE-corrected, p < 0.05). Being born preterm is associated with poorer performance in various cognitive domains (i.e., phonetic and semantic fluencies, and theory of mind) later in life, along with differences in normative structural brain development in inferior temporal gyrus and regional white matter microstructure.

Indexed as

BrainCognitionAdolescentAdultFemaleGestational AgeHumansInfant, NewbornInfant, PrematureMagnetic Resonance ImagingMaleNeuropsychological TestsPremature BirthYoung AdultAdolescence and young adulthoodBrain macro and microstructureCognitive functioningCurrent socioeconomic statusLow-risk preterm birth

Identifiers

PMID39256424
PMCPMC11387778

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.