Evidence map›Paper›PMID 39256377›Full record

ArticleNature communications2024

Inflammation-free electrochemical in vivo sensing of dopamine with atomic-level engineered antioxidative single-atom catalyst.

Xiaolong Gao, Huan Wei, Wenjie Ma, Wenjie Wu, Wenliang Ji, Junjie Mao, Ping Yu, Lanqun Mao

Abstract read
In one paragraph

Article in Nature communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers.

0numbers the graph read from it
0cells of the map it votes in
14citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

14 citing papers in PubMed.

  1. Single-Atom-Enhanced Fully Inkjet-Printed Electrochemical Sensor for Dopamine Detection.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Galvanically Deposited FeChemistry, an Asian journal · 2026
    Article
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  6. Photocatalytically Activated Cu-NAdvanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Xiaolong Gao *College of Chemistry, Beijing Normal University, 100875, Beijing, China.
Huan Wei *College of Chemistry, Beijing Normal University, 100875, Beijing, China.
Wenjie MaBeijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, The Chinese Academy of Sciences (CAS), 100190, Beijing, China. mawenjie@iccas.ac.cn.ORCID 0000-0003-1268-4959
Wenjie WuBeijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, The Chinese Academy of Sciences (CAS), 100190, Beijing, China.
Wenliang JiCollege of Chemistry, Beijing Normal University, 100875, Beijing, China.
Junjie MaoCollege of Chemistry and Materials Science, Anhui Normal University, Wuhu, 241002, China.ORCID 0000-0003-0223-7119
Ping YuBeijing National Laboratory for Molecular Sciences, Key Laboratory of Analytical Chemistry for Living Biosystems, Institute of Chemistry, The Chinese Academy of Sciences (CAS), 100190, Beijing, China. yuping@iccas.ac.cn.ORCID 0000-0002-6096-1933
Lanqun MaoCollege of Chemistry, Beijing Normal University, 100875, Beijing, China. lqmao@bnu.edu.cn.ORCID 0000-0001-8286-9321

Funding

National Natural Science Foundation of China (National Science Foundation of China) 22125406 and 22074149National Natural Science Foundation of China (National Science Foundation of China) 22134002Natural Science Foundation of Beijing Municipality (Beijing Natural Science Foundation) 2242028Natural Science Foundation of Beijing Municipality (Beijing Natural Science Foundation) Z230022
6 · The paper itself

Abstract

Electrochemical methods with tissue-implantable microelectrodes provide an excellent platform for real-time monitoring the neurochemical dynamics in vivo due to their superior spatiotemporal resolution and high selectivity and sensitivity. Nevertheless, electrode implantation inevitably damages the brain tissue, upregulates reactive oxygen species level, and triggers neuroinflammatory response, resulting in unreliable quantification of neurochemical events. Herein, we report a multifunctional sensing platform for inflammation-free in vivo analysis with atomic-level engineered Fe single-atom catalyst that functions as both single-atom nanozyme with antioxidative activity and electrode material for dopamine oxidation. Through high-temperature pyrolysis and catalytic performance screening, we fabricate a series of Fe single-atom nanozymes with different coordination configurations and find that the Fe single-atom nanozyme with FeN

Indexed as

AntioxidantsDopamineElectrochemical TechniquesOxidation-ReductionAnimalsBiosensing TechniquesBrainCatalaseCatalysisInflammationIronMaleMicroelectrodesRatsRats, Sprague-DawleySuperoxide DismutaseAntioxidantsCatalaseDopamineIronSuperoxide Dismutase

Identifiers

PMID39256377
PMCPMC11387648

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.