Evidence map›Paper›PMID 39256327›Full record

ArticleJournal of medical toxicology : official journal of the American College of Medical Toxicology2024

The Toxicology Investigators Consortium 2023 Annual Report.

Adrienne Hughes, Alexandra Amaducci, Sharan L Campleman, Shao Li, Mari Costantini, Meghan B Spyres, Hannah Spungen, Jessica Kent, Alyssa Falise, Rachel Culbreth and 4 more

Abstract read
In one paragraph

Article in Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Observational
  2. Drug Critical Limits for Urgent Physician Notification.Clinical pharmacology and therapeutics · 2026
    Article
  3. The Toxicology Investigators Consortium 2024 Annual Report.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2026
    Article
  4. Article
  5. The Value of Medical Toxicologists.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors.

Adrienne HughesDepartment of Emergency Medicine, Oregon Health and Science University, 3181 SW Sam Jackson Park Rd, Portland, OR, 97239, USA.
Alexandra AmaducciDepartment of Emergency and Hospital Medicine, Lehigh Valley Health Network, 2545 Schoenersville Rd, Bethlehem, PA, 18017, USA.
Sharan L CamplemanAmerican College of Medical Toxicology, 10645 N Tatum Blvd., Suite 200-111, Phoenix, AZ, 85028, USA.
Shao LiAmerican College of Medical Toxicology, 10645 N Tatum Blvd., Suite 200-111, Phoenix, AZ, 85028, USA.
Mari CostantiniAmerican College of Medical Toxicology, 10645 N Tatum Blvd., Suite 200-111, Phoenix, AZ, 85028, USA.
Meghan B SpyresDepartment of Medical Toxicology, Banner - University Medical Center, 1111 E McDowell Rd. Building A, Phoenix, AZ, 85006, USA.
Hannah SpungenDepartment of Medical Toxicology, Banner - University Medical Center, 1111 E McDowell Rd. Building A, Phoenix, AZ, 85006, USA.
Jessica KentDivision of Clinical Pharmacology & Toxicology, Department of Medicine, University of Toronto, 6 Queen's Park Crescent West, Toronto, ON, M5S 3H2, Canada.
Alyssa FaliseAmerican College of Medical Toxicology, 10645 N Tatum Blvd., Suite 200-111, Phoenix, AZ, 85028, USA.
Rachel CulbrethAmerican College of Medical Toxicology, 10645 N Tatum Blvd., Suite 200-111, Phoenix, AZ, 85028, USA. Rachel.Culbreth@acmt.net.ORCID 0000-0002-5270-2608
Paul M WaxAmerican College of Medical Toxicology, 10645 N Tatum Blvd., Suite 200-111, Phoenix, AZ, 85028, USA.
Jeffery BrentUniversity of Colorado School of Medicine, 13001 E 17th Pl, Aurora, CO, 80045, USA.
Kim AldyAmerican College of Medical Toxicology, 10645 N Tatum Blvd., Suite 200-111, Phoenix, AZ, 85028, USA.
Toxicology Investigators Consortium Study Group

Funding

American Academy of Addiction Psychiatry 1H79TI085588NCIPC CDC HHS 75D30120C07819U.S. Food and Drug Administration 75F40122D00028
6 · The paper itself

Abstract

Since 2010, the American College of Medical Toxicology (ACMT) Toxicology Investigators Consortium (ToxIC) has maintained the ToxIC Core Registry, a national case registry of in-hospital and clinic patient consultations submitted by medical toxicology physicians. Deidentified patient data entered into the registry includes patient demographics, reason for medical toxicology evaluation, exposure agents, clinical signs and symptoms, treatments and antidotes administered, and mortality. This fourteenth annual report provides data from 7392 patients entered into the Core Registry in 2023 by 36 participating sites comprising 61 distinct healthcare facilities, bringing the total case count to 102331 between 2010 and 2023. Ethanol was the most commonly reported exposure agent class (24.4%), followed by opioids (22.7%), non-opioid analgesics (16.7%), and antidepressants (11.7%). For the first time since the registry's initiation, in 2023, ethanol was the leading agent of exposure. There were 98 fatalities (case fatality rate of 1.3%). Additional descriptive analyses in this annual report were conducted to describe the reasons for medical toxicology consultation by age in 2023, and yearly trends for opioid and psychoactive exposures, physostigmine and rivastigmine treatments, and acetaminophen exposures treated with fomepizole.

Indexed as

PoisoningRegistriesToxicologyAdolescentAdultAgedAged, 80 and overAntidotesChildChild, PreschoolFemaleHumansInfantMaleMiddle AgedUnited StatesAntidotesEpidemiologyMedical ToxicologyOverdosePoisoningSurveillance

Identifiers

PMID39256327
PMCPMC11436580

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.