Evidence map›Paper›PMID 39255106›Full record

ArticleIEEE transactions on visualization and computer graphics2025

KnowNet: Guided Health Information Seeking from LLMs via Knowledge Graph Integration

Youfu Yan, Yu Hou, Yongkang Xiao, Rui Zhang, Qianwen Wang

Abstract read
In one paragraph

Article in IEEE transactions on visualization and computer graphics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Review
  2. Review
  3. A Survey on Unifying Large Language Models and Knowledge Graphs for Biomedicine and Healthcare.KDD : proceedings. International Conference on Knowledge Discovery & Data Mining · 2025
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Youfu Yan
Yu Hou
Yongkang Xiao
Rui Zhang
Qianwen Wang

Funding

Detecting synergistic effects of pharmacological and non-pharmacological interventions for AD/ADRDR01AG078154 · NIA · UNIVERSITY OF MINNESOTA · PI HUA XU, RUI ZHANG · 2022 to 2026
$4.2M
A Translational Informatics Framework to Mine Efficacy and Safety of Dietary SupplementsR01AT009457 · NCCIH · UNIVERSITY OF MINNESOTA · PI RUI ZHANG · 2017 to 2026
$4.1M
SCH: A New Computational Framework for Learning from Imbalanced Biomedical DataR01CA287413 · NCI · UNIVERSITY OF MINNESOTA · PI CUI, YING, SUN, JU · 2023 to 2025
$1.2M
NCCIH NIH HHS R01 AT009457NCI NIH HHS R01 CA287413NIA NIH HHS R01 AG078154
6 · The paper itself

Abstract

The increasing reliance on Large Language Models (LLMs) for health information seeking can pose severe risks due to the potential for misinformation and the complexity of these topics. This paper introduces KnowNet a visualization system that integrates LLMs with Knowledge Graphs (KG) to provide enhanced accuracy and structured exploration. Specifically, for enhanced accuracy, KnowNet extracts triples (e.g., entities and their relations) from LLM outputs and maps them into the validated information and supported evidence in external KGs. For structured exploration, KnowNet provides next-step recommendations based on the neighborhood of the currently explored entities in KGs, aiming to guide a comprehensive understanding without overlooking critical aspects. To enable reasoning with both the structured data in KGs and the unstructured outputs from LLMs, KnowNet conceptualizes the understanding of a subject as the gradual construction of graph visualization. A progressive graph visualization is introduced to monitor past inquiries, and bridge the current query with the exploration history and next-step recommendations. We demonstrate the effectiveness of our system via use cases and expert interviews.

Identifiers

PMID39255106
PMCPMC11875928

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.