Evidence map›Paper›PMID 39255070›Full record

ArticleACS applied bio materials2024

Low Silver/Copper Exchange in a Copper-Phosphate Enzyme Nanoflower Hybrid Extremely Enhanced Antimicrobial Efficacy against Multidrug Resistant Bacteria.

Clara Ortega-Nieto, Noelia Losada-Garcia, Pilar Domingo-Calap, Miroslawa Pawlyta, Jose M Palomo

Abstract read
In one paragraph

Article in ACS applied bio materials, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Clara Ortega-NietoInstituto de Catálisis y Petroleoquímica (ICP), CSIC, 28049 Madrid, Spain.ORCID 0000-0002-2115-4944
Noelia Losada-GarciaInstituto de Catálisis y Petroleoquímica (ICP), CSIC, 28049 Madrid, Spain.
Pilar Domingo-CalapInstitute for Integrative Systems Biology (I2SysBio), Universitat de València-CSIC, 46980 Paterna, Spain.
Miroslawa PawlytaMaterials Research Laboratory, Faculty of Mechanical Engineering, Silesian University of Technology, Konarskiego 18A, 44-100 Gliwice, Poland.
Jose M PalomoInstituto de Catálisis y Petroleoquímica (ICP), CSIC, 28049 Madrid, Spain.ORCID 0000-0002-6464-1216

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infections caused by bacteria that are resistant to many drugs are a major threat to public health in many countries around the world. Here we demonstrate the creation of heterogeneous catalytic nanomaterials with outstanding antimicrobial properties against several superbugs. We have shown that replacing a small amount of copper in a generated copper-phosphate-enzyme nanoflower hybrid with silver drastically increases the antimicrobial capacity of the nanomaterial. In this sense, it has been confirmed that the exchange generated silver phosphate nanoparticles on the Cu nanoflowers, with control of the nanoparticle diameter size. The Fenton catalytic activity of the Ag-containing nanobiohybrids was affected, showing better performance with lower amounts of silver in the final hybrid. This effect was confirmed by their antimicrobial efficacy against

Indexed as

Anti-Bacterial AgentsCopperMicrobial Sensitivity TestsParticle SizeSilverBiocompatible MaterialsDrug Resistance, Multiple, BacterialEscherichia coliMaterials TestingPhosphatesPseudomonas aeruginosaAnti-Bacterial AgentsBiocompatible MaterialsCopperPhosphatesSilverantimicrobial activityenzyme−metal biohybridsmultidrug resistant bacteriananoparticlessilver

Identifiers

PMID39255070
PMCPMC11497203

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.