Evidence map›Paper›PMID 39254895›Full record

ArticleClinical journal of gastroenterology2024

Diffuse large B-cell lymphoma of the gallbladder with hepatoduodenal invasion exhibiting a necrotic tendency.

Hironao Matsumoto, Shunsuke Horitani, Yutaro Tokutomi, Masataka Kano, Masahiro Orino, Kanehiko Suwa, Masahiro Takeo, Toshiyuki Mitsuyama, Takeshi Yamashina, Masaaki Shimatani

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In one paragraph

Article in Clinical journal of gastroenterology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Hironao MatsumotoDivision of Gastroenterology and Hepatology, the Third Department of Internal Medicine, Kansai Medical University Medical Center, 10-15 Fumizonocho, Moriguchi, Osaka, 570-8507, Japan.
Shunsuke HoritaniDivision of Gastroenterology and Hepatology, the Third Department of Internal Medicine, Kansai Medical University Medical Center, 10-15 Fumizonocho, Moriguchi, Osaka, 570-8507, Japan. horitash@hirakata.kmu.ac.jp.ORCID http://orcid.org/0000-0002-8413-6110
Yutaro TokutomiDivision of Gastroenterology and Hepatology, the Third Department of Internal Medicine, Kansai Medical University Medical Center, 10-15 Fumizonocho, Moriguchi, Osaka, 570-8507, Japan.
Masataka KanoDivision of Gastroenterology and Hepatology, the Third Department of Internal Medicine, Kansai Medical University Medical Center, 10-15 Fumizonocho, Moriguchi, Osaka, 570-8507, Japan.
Masahiro OrinoDivision of Gastroenterology and Hepatology, the Third Department of Internal Medicine, Kansai Medical University Medical Center, 10-15 Fumizonocho, Moriguchi, Osaka, 570-8507, Japan.
Kanehiko SuwaDivision of Gastroenterology and Hepatology, the Third Department of Internal Medicine, Kansai Medical University Medical Center, 10-15 Fumizonocho, Moriguchi, Osaka, 570-8507, Japan.
Masahiro TakeoDivision of Gastroenterology and Hepatology, the Third Department of Internal Medicine, Kansai Medical University Medical Center, 10-15 Fumizonocho, Moriguchi, Osaka, 570-8507, Japan.
Toshiyuki MitsuyamaDivision of Gastroenterology and Hepatology, the Third Department of Internal Medicine, Kansai Medical University Medical Center, 10-15 Fumizonocho, Moriguchi, Osaka, 570-8507, Japan.
Takeshi YamashinaDivision of Gastroenterology and Hepatology, the Third Department of Internal Medicine, Kansai Medical University Medical Center, 10-15 Fumizonocho, Moriguchi, Osaka, 570-8507, Japan.
Masaaki ShimataniDivision of Gastroenterology and Hepatology, the Third Department of Internal Medicine, Kansai Medical University Medical Center, 10-15 Fumizonocho, Moriguchi, Osaka, 570-8507, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We report a case of diffuse large B-cell lymphoma (DLBCL) of the gallbladder with extensive hepatoduodenal invasion, which was challenging to diagnose histologically due to a strong tendency to be necrotic. An 71 year-old man presented with upper abdominal pain and was referred to our hospital. Computed tomography revealed a distended gallbladder with air within the irregular gallbladder wall and an indistinct border with the hepatoduodenum, suggesting invasion. Esophagogastroduodenoscopy detected an ulceration in the duodenal bulb. However, histologic analysis failed to provide a definitive diagnosis due to the presence of necrotic tissue. Furthermore, direct biopsy from the gallbladder mucosa by endoscopic retrograde cholangiography revealed only necrotic tissue and no diagnosis. Contrast ultrasonography for the hepatic invasion revealed enhancement with blood flow, suggesting non-necrotic tissue. Subsequently, an ultrasound-guided core-needle biopsy was conducted to obtain tissue samples from the described lesion. The pathology showed atypical lymphocytes with irregular nuclei. Immunostaining indicated positive expression of CD10, CD20, Bcl-6, and C-Myc, consistent with a diagnosis of DLBCL. In our case, the lymphoma exhibited a strong tendency to be necrotic, making histologic diagnosis difficult. However, selective biopsy from the site of blood flow made the diagnosis possible and proved to be useful.

Indexed as

Gallbladder NeoplasmsLymphoma, Large B-Cell, DiffuseNecrosisNeoplasm InvasivenessAgedDuodenal NeoplasmsHumansLiver NeoplasmsMaleTomography, X-Ray ComputedDiffuse large B-cell lymphomaGallbladder lymphomaHepatoduodenal invasionTumor necrosis

Identifiers

PMID39254895

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.