ArticleIntensive care medicine2024
Fluid responsiveness in acute respiratory distress syndrome patients: a post hoc analysis of the HEMOPRED study.
Article in Intensive care medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
7 citing papers in PubMed.
- The Acute Respiratory Distress Syndrome (ARDS): epidemiology, etiology, molecular mechanisms, diagnosis and therapeutic strategies.Molecular biomedicine · 2026Review
- Fluid responsiveness in ARDS: current evidence, knowledge gaps, and future directions - a scoping review of the literature.BMC anesthesiology · 2026Article
- Ten Influential Point-of-Care Ultrasound Papers: 2025 in Review.Journal of intensive care medicine · 2026Review
- Update on acute respiratory failure.Intensive care medicine · 2026Article
- Bedside thoracic echography in ICU: new insights for acute circulatory and respiratory failure.Intensive care medicine · 2026Review
- Lack of preload responsiveness may determine poor clinical outcomes in mechanically ventilated patients with ARDS.Critical care (London, England) · 2025Observational
- The Five Pillars of Acute Right Ventricular Heart Failure Therapy: Can We Keep the Pediment in Balance?Journal of clinical medicine · 2024Article
Corrections and comments
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeOptimal fluid management in patients with acute respiratory distress syndrome (ARDS) is challenging due to risks associated with both circulatory failure and fluid overload. The performance of dynamic indices to predict fluid responsiveness (FR) in ARDS patients is uncertain.
methodsThis post hoc analysis of the HEMOPRED study compared the performance of dynamic indices in mechanically ventilated patients with shock, with and without ARDS, to predict FR, defined as an increase in aortic velocity time integral (VTI) > 10% after passive leg raising (PLR).
resultsAmong 540 patients, 117 (22%) had ARDS and were ventilated with a median tidal volume of 7.6 mL/kg [6.9-8.4] and a median positive end-expiratory pressure of 7 cmH
conclusionPerformance of dynamic indices to predict FR appears preserved in ARDS patients, albeit with distinct thresholds. Hypovolemia, indicated by a > 32% increase in aortic VTI during PLR, rather than FR, was associated with ICU mortality in this population.
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