Evidence map›Paper›PMID 39254529›Full record

ArticleJournal of the American Medical Informatics Association : JAMIA2024

Navigating electronic health record accuracy by examination of sex incongruent conditions.

Ling Cai, Ralph J DeBerardinis, Xiaowei Zhan, Guanghua Xiao, Yang Xie

Abstract read
In one paragraph

Article in Journal of the American Medical Informatics Association : JAMIA, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ling CaiQuantitative Biomedical Research Center, Peter O'Donnell Jr. School of Public Health, University of Texas Southwestern Medical Center, Dallas, TX 75390, United States.ORCID 0000-0002-8592-5269
Ralph J DeBerardinisChildren's Research Institute, University of Texas Southwestern Medical Center, Dallas, TX 75390, United States.ORCID 0000-0002-2705-7432
Xiaowei ZhanQuantitative Biomedical Research Center, Peter O'Donnell Jr. School of Public Health, University of Texas Southwestern Medical Center, Dallas, TX 75390, United States.ORCID 0000-0002-6249-7193
Guanghua XiaoQuantitative Biomedical Research Center, Peter O'Donnell Jr. School of Public Health, University of Texas Southwestern Medical Center, Dallas, TX 75390, United States.ORCID 0000-0001-9387-9883
Yang XieQuantitative Biomedical Research Center, Peter O'Donnell Jr. School of Public Health, University of Texas Southwestern Medical Center, Dallas, TX 75390, United States.

Funding

Technology to Empower Changes in Health (TECH) Network Participant Technologies CenterU24OD023176 · OD · SCRIPPS RESEARCH INSTITUTE, THE · PI TOPOL, ERIC JEFFREY · 2016 to 2022
$204.7M
Precision Medicine Initiative Cohort Program BiobankU24OD023121 · OD · MAYO CLINIC ROCHESTER · PI CEKANOVA, MARIA, CICEK, MINE · 2016 to 2024
$185.5M
Enhancing All of Us Data Resources for Nutrition Precision Health: the All of Us Data and Research CenterU2COD023196 · OD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI GLAZER, DAVID, HARRIS, PAUL A. · 2016 to 2022
$143.7M
Adaptive Platform for Personalized EngagementU24OD023163 · OD · VIGNET, INC. · PI JAIN, PRADUMAN · 2017 to 2020
$102.6M
University of Arizona-Banner Health All of Us Research Program OT2OD026549 · OD · UNIVERSITY OF ARIZONA · PI MORENO, FRANCISCO A, REIMAN, ERIC MICHAEL · 2018 to 2023
$78.9M
California Precision Medicine Research Program ConsortiumOT2OD026552 · OD · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ANTON-CULVER, HODA A, OHNO-MACHADO, LUCILA · 2018 to 2023
$73.4M
All of Us PennsylvaniaOT2OD026554 · OD · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI REIS, STEVEN E, VISWESWARAN, SHYAM · 2018 to 2023
$72.1M
New York City Consortium for Precision MedicineOT2OD026556 · OD · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI BIER, LOUISE E, GHARAVI, ALI G · 2018 to 2023
$67.3M
SouthEast Enrollment Center (SEEC) OT2OD026551 · OD · UNIVERSITY OF MIAMI SCHOOL OF MEDICINE · PI CARRASQUILLO, OLVEEN, COLON, VIVIAN · 2018 to 2023
$62.8M
Southern All of Us NetworkOT2OD026548 · OD · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI FOUAD, MONA N., KORF, BRUCE R · 2018 to 2023
$60.5M
Illinois Precision Medicine Consortium OT2OD026557 · OD · NORTHWESTERN UNIVERSITY AT CHICAGO · PI AHSAN, HABIBUL, ARGOS, MARIA · 2018 to 2023
$60.5M
The New England Precision Medicine Consortium of the All of Us Research ProgramOT2OD026553 · OD · MASSACHUSETTS GENERAL HOSPITAL · PI CLARK, CHERYL RENEE, KARLSON, ELIZABETH W · 2018 to 2023
$58.8M
Communications and Engagement 3 OT2 OD023205Data and Research Center 5 U2C OD023196Federally Qualified Health Centers HHSN 263201600085UHoward Hughes Medical InstituteHoward Hughes Medical Institute Investigator ProgramNCI NIH HHS R35 CA220449NCI NIH HHS U01 CA213338NCI NIH HHS U01 CA249245NIAID NIH HHS U01 AI156189NIAID NIH HHS U01 AI169298NIDCR NIH HHS R01 DE030656NIGMS NIH HHS R01 GM141519NIGMS NIH HHS R35 GM136375NIHNIH R35CA22044901NIH HHS OT2 OD023206NIH HHS OT2 OD025276NIH HHS OT2 OD025277NIH HHS OT2 OD025315NIH HHS OT2 OD025337NIH HHS OT2 OD026548NIH HHS OT2 OD026549NIH HHS OT2 OD026550NIH HHS OT2 OD026551NIH HHS OT2 OD026552NIH HHS OT2 OD026553NIH HHS OT2 OD026554NIH HHS OT2 OD026555NIH HHS OT2 OD026556NIH HHS OT2 OD026557NIH HHS R01GM140012NIH HHS U24 OD023121NIH HHS U24 OD023163NIH HHS U24 OD023176ODCDC CDC HHS U24 OD023176Participant Technology Systems Center 1 U24 OD023163
6 · The paper itself

Abstract

objectiveThe increasing reliance on electronic health records (EHRs) for research and clinical care necessitates robust methods for assessing data quality and identifying inconsistencies. To address this need, we develop and apply the incongruence rate (IR) using sex-specific medical conditions. We also characterized participants with incongruent records to better understand the scope and nature of data discrepancies. MATERIALS AND

methodsIn this cross-sectional study, we used the All of Us Research Program's latest version 7 (v7) EHR data to identify prevalent sex-specific conditions and evaluated the occurrence of incongruent cases, quantified as IR.

resultsAmong the 92 597 males and 152 551 females with condition occurrence data available from All of Us and sex-conformed gender, we identified 167 prevalent sex-specific conditions. Among the 37 537 biological males and 95 499 biological females with these sex-specific conditions, we detected an overall IR of 0.86%. Attempt to include non-cisgender participants result in inflated overall IR. Additionally, a significant proportion of participants with incongruent conditions also presented with conditions congruent to their biological sex, indicating a mix of accurate and erroneous records. These incongruences were not geographically or temporally isolated, suggesting systematic issues in EHR data integrity. DISCUSSION: Our findings call attention to the existence of systemic data incongruences in sex-specific conditions and the need for robust validation checks. Extending IR evaluation to non-cisgender participants or non-sex-based conditions remain a challenge.

conclusionThe sex condition-specific IR, when applied to adult populations, provides a valuable metric for data quality assessment in EHRs.

Indexed as

Data AccuracyElectronic Health RecordsAdolescentAdultAgedCross-Sectional StudiesFemaleHumansMaleMiddle AgedSex FactorsUnited StatesYoung AdultAll of Usdisconcordantelectronic health recordsquality assessmentsex

Identifiers

PMID39254529
PMCPMC11631140

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.