Evidence map›Paper›PMID 39254477›Full record

ArticleMolecular carcinogenesis2024

Monoubiquitinated H2B, a Main Chromatin Target of Formaldehyde, Is Important for S-Phase Checkpoint Signaling and Genome Stability.

Sasmita Mishra, Casey Krawic, Michal W Luczak, Anatoly Zhitkovich

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Molecular carcinogenesis, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Sasmita MishraDepartment Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island, USA.
Casey KrawicDepartment Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island, USA.
Michal W LuczakUnlocked Labs, Laramie, Wyoming, USA.
Anatoly ZhitkovichDepartment Pathology and Laboratory Medicine, Brown University, Providence, Rhode Island, USA.ORCID 0000-0001-9007-2400

Funding

Regulation of p53 and Checkpoint Signaling by Chromium(VI)R01ES028072 · NIEHS · BROWN UNIVERSITY · PI ZHITKOVICH, ANATOLY · 2018 to 2022
$1.8M
Indirect Genotoxicity in Metal CarcinogenesisR01ES031002 · NIEHS · BROWN UNIVERSITY · PI ZHITKOVICH, ANATOLY · 2020 to 2024
$1.8M
Nickel and toxic topoisomerase I productsR01ES031979 · NIEHS · BROWN UNIVERSITY · PI ZHITKOVICH, ANATOLY · 2021 to 2025
$1.8M
NIEHS NIH HHS R01 ES028072NIEHS NIH HHS R01 ES031002NIEHS NIH HHS R01 ES031979This study was supported by the National Institute of Environmental Health Sciences (Grants ES031979, ES031002, and ES028072).
6 · The paper itself

Abstract

Formaldehyde (FA) is a human carcinogen with ubiquitous environmental exposures and significant endogenous formation. Genotoxic activity of FA stems from its reactivity with DNA-NH

Indexed as

ChromatinDNA DamageFormaldehydeGenomic InstabilityHistonesSignal TransductionUbiquitinationHumansProtein Processing, Post-TranslationalS Phase Cell Cycle CheckpointsChromatinFormaldehydeHistonesaldehydescarcinogenesiscell cyclechromatin damagegenome instability

Identifiers

PMID39254477
PMCPMC11567799

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.