ReviewAsian journal of andrology2024
Histopathological evaluation and grading for prostate cancer: current issues and crucial aspects.
Review in Asian journal of andrology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Raman spectroscopic signatures of prostate cancer progression: correlation with gleason score.Molecular and cellular biochemistry · 2026Article
- PTEN Protein Loss in Diagnostic Prostate Biopsies Is Associated with Gleason Score Upgrading in Radical Prostatectomy.Cancers · 2026Article
- Bias and Fairness Across the Healthcare AI Lifecycle: A Clinician-Oriented Review.Balkan medical journal · 2026Review
- Article
- LncRNA expression in prostate cancer: FromNon-coding RNA research · 2026Article
- Whole-mount histopathology as spatial ground truth for artificial intelligence in prostate cancer: a structured narrative review of techniques, models, and translational gaps.American journal of clinical and experimental urology · 2026Review
- Artificial intelligence in prostate biopsy: diagnostic applications, risk stratification, and precision oncology.Frontiers in oncology · 2026Review
- Impact of prognostic nutritional index and geriatric nutritional risk index on prognosis in elderly patients with early-stage prostate cancer.Frontiers in nutrition · 2026Article
- Incremental value of prostate-specific antigen density beyond PI-RADS and conventional MRI features for predicting the highest ISUP grade group in patients with prostate cancer diagnosed at initial systematic prostate biopsy.American journal of cancer research · 2026Article
- Methylation-based signature to distinguish indolent and aggressive prostate cancer.Biology open · 2025Article
- Intraductal carcinoma of the prostate: A comprehensive literature review focused on grading challenges and controversies.Histology and histopathology · 2025Review
- Cribriform pattern and IDC-P in prostate biopsies: prognostic relevance and reporting in metastatic disease.The journal of pathology. Clinical research · 2025Article
- Assessment of interobserver variability in Gleason grading for prostate carcinoma.Northern clinics of Istanbul · 2025Article
- Inflammatory-based prognostic indicators in prostate cancer: evaluating NLR, PLR, and SII in relation to Cambridge and ISUP classifications.Frontiers in oncology · 2025Article
- Fractal dimensions for tumour-related cell types of prostate cancer on histopathology images using multiple-threshold box counting algorithm.Biophysics and physicobiology · 2025Article
- The continued pursuit of new strategies and new technologies.Asian journal of andrology · 2024Article
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2 authors.
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Abstract
abstractA crucial aspect of prostate cancer grading, especially in low- and intermediate-risk cancer, is the accurate identification of Gleason pattern 4 glands, which includes ill-formed or fused glands. However, there is notable inconsistency among pathologists in recognizing these glands, especially when mixed with pattern 3 glands. This inconsistency has significant implications for patient management and treatment decisions. Conversely, the recognition of glomeruloid and cribriform architecture has shown higher reproducibility. Cribriform architecture, in particular, has been linked to the worst prognosis among pattern 4 subtypes. Intraductal carcinoma of the prostate (IDC-P) is also associated with high-grade cancer and poor prognosis. Accurate identification, classification, and tumor size evaluation by pathologists are vital for determining patient treatment. This review emphasizes the importance of prostate cancer grading, highlighting challenges like distinguishing between pattern 3 and pattern 4 and the prognostic implications of cribriform architecture and intraductal proliferations. It also addresses the inherent grading limitations due to interobserver variability and explores the potential of computational pathology to enhance pathologist accuracy and consistency.
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