Evidence map›Paper›PMID 39254346›Full record

ArticleInfection and immunity2024

Pathogenic diversification of the gut commensal

Jessica A Klein, Alexander V Predeus, Aimee R Greissl, Mattie M Clark-Herrera, Eddy Cruz, Jennifer A Cundiff, Amanda L Haeberle, Maya Howell, Aaditi Lele, Donna J Robinson and 10 more

Abstract read
In one paragraph

Article in Infection and immunity, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Article
  3. CanineMicrobial genomics · 2026
    Article
  4. The Gut Microbiota ofMicroorganisms · 2025
    Review
  5. Article
  6. Wild raccoons (Microbiology spectrum · 2025
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

20 authors.

Jessica A KleinPaul G. Allen School for Global Health, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA.ORCID 0000-0002-0529-9406
Alexander V PredeusWellcome Sanger Institute, Hinxton, Cambridgeshire, United Kingdom.ORCID 0000-0002-2750-1599
Aimee R GreisslPaul G. Allen School for Global Health, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA.
Mattie M Clark-Herrera *Paul G. Allen School for Global Health, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA.
Eddy Cruz *Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Jennifer A Cundiff *Paul G. Allen School for Global Health, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA.
Amanda L Haeberle *Paul G. Allen School for Global Health, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA.
Maya Howell *Paul G. Allen School for Global Health, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA.
Aaditi Lele *Paul G. Allen School for Global Health, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA.
Donna J Robinson *Paul G. Allen School for Global Health, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA.
Trina L Westerman *Department of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Marie Wrande *Paul G. Allen School for Global Health, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA.
Sarah J Wright *Paul G. Allen School for Global Health, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA.
Nicole M GreenPublic Health Laboratory, Los Angeles County Department of Public Health, Downey, California, USA.ORCID 0000-0001-9745-0240
Bruce A VallanceDivision of Gastroenterology, Hepatology and Nutrition, BC Children's Hospital and the University of British Columbia, Vancouver, British Columbia, Canada.
Michael McClellandDepartment of Microbiology and Molecular Genetics, University of California, Irvine, California, USA.ORCID 0000-0003-1788-9347
Andres MejiaComparative Pathology Laboratory, Research Animal Resources and Compliance, University of Wisconsin-Madison, Madison, Wisconsin, USA.
Alan G GoodmanPaul G. Allen School for Global Health, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA.ORCID 0000-0001-6394-332X
Johanna R ElfenbeinDepartment of Pathobiological Sciences, School of Veterinary Medicine, University of Wisconsin-Madison, Madison, Wisconsin, USA.ORCID 0000-0002-4764-0713
Leigh A KnodlerPaul G. Allen School for Global Health, College of Veterinary Medicine, Washington State University, Pullman, Washington, USA.ORCID 0000-0002-3028-2198

Funding

Epithelial intrinsic inflammasomes direct host defense against gut microbesR01AI134766 · NIAID · WASHINGTON STATE UNIVERSITY · PI KNODLER, LEIGH · 2018 to 2022
$2.2M
An Interdisciplinary Training Program to Transform Graduate Education In Genetics and GenomicsT32GM140936 · NIGMS · UNIVERSITY OF MINNESOTA · PI ALBERT, FRANK WOLFGANG, GREENSTEIN, DAVID IRWIN · 2021 to 2025
$851k
Vacuole lysis by type III translocator proteinsR21AI130645 · NIAID · WASHINGTON STATE UNIVERSITY · PI KNODLER, LEIGH · 2018 to 2019
$421k
NIAID NIH HHS R01 AI134766NIAID NIH HHS R21 AI130645NIGMS NIH HHS T32 GM140936
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

ProvidenciaType III Secretion SystemsAnimalsBacterial ProteinsCattleEnterobacteriaceae InfectionsHumansInflammasomesVirulence FactorsBacterial ProteinsInflammasomesType III Secretion SystemsVirulence Factorsdiarrheaenteric bacteriapathogenesistype III secretionvirulence

Identifiers

PMID39254346
PMCPMC11477908

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.