Evidence map›Paper›PMID 39254087›Full record

ArticleAmerican journal of physiology. Lung cellular and molecular physiology2024

The pH-sensitive translocation of V-ATPase in the small airway of cystic fibrosis pigs.

Raul Villacreses, Ian M Thornell, Xiaopeng Li, Steven E Mather, Jimena Urbano, David A Stoltz, Joseph Zabner

Abstract read
In one paragraph

Article in American journal of physiology. Lung cellular and molecular physiology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Raul VillacresesDepartment of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States.ORCID 0000-0002-9928-0182
Ian M ThornellDepartment of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States.ORCID 0000-0001-5535-2925
Xiaopeng LiDepartment of Pediatrics and Human Development, College of Human Medicine, Michigan State University, Grand Rapids, Michigan, United States.
Steven E MatherDepartment of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States.ORCID 0000-0003-4183-9358
Jimena UrbanoDepartment of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States.ORCID 0009-0008-9484-0524
David A StoltzDepartment of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States.ORCID 0000-0003-0893-9015
Joseph ZabnerDepartment of Internal Medicine, Roy J. and Lucille A. Carver College of Medicine, University of Iowa, Iowa City, Iowa, United States.ORCID 0000-0002-9606-1339

Funding

Pulmonary Toxicology Facility CoreP30ES005605 · NIEHS · UNIVERSITY OF IOWA · PI Jong Sung Kim · 1990 to 2026
$40.5M
Respiratory virus infection in early cystic fibrosis lung diseaseP01HL091842 · NHLBI · UNIVERSITY OF IOWA · PI ZABNER, JOSEPH · 2008 to 2022
$34.2M
CTSA K12 Program at The University of IowaK12TR004382 · NCATS · UNIVERSITY OF IOWA · PI ALEXANDER G BASSUK, Polly J Ferguson · 2023 to 2026
$3.0M
Role of disrupted ASL pH regulation in small airways in CF lung disease pathogenesisR01HL153165 · NHLBI · MICHIGAN STATE UNIVERSITY · PI LI, XIAOPENG · 2021 to 2024
$2.2M
HHS | NIH | National Center for Advancing Translational Sciences (NCATS) 1K12TR004382-01HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) HL091842HHS | NIH | National Heart, Lung, and Blood Institute (NHLBI) HL153165-01A1NCATS NIH HHS K12 TR004382NIEHS NIH HHS P30 ES005605
6 · The paper itself

Abstract

In contrast to pig large airways, the pH of airway surface liquid (ASL) in pig small airways is regulated by CFTR-mediated HCO

Indexed as

Cystic FibrosisVacuolar Proton-Translocating ATPasesAnimalsCystic Fibrosis Transmembrane Conductance RegulatorHydrogen-Ion ConcentrationLungMacrolidesMiceProtein TransportRespiratory MucosaSwinebafilomycin A1Cystic Fibrosis Transmembrane Conductance RegulatorMacrolidesVacuolar Proton-Translocating ATPasesairway surface liquidcystic fibrosispHsmall airwaysV-ATPase

Identifiers

PMID39254087
PMCPMC11563583

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.