ArticleThe Lancet regional health. Europe2024
Body mass index and risk of over 100 cancer forms and subtypes in 4.1 million individuals in Sweden: the Obesity and Disease Development Sweden (ODDS) pooled cohort study.
Article in The Lancet regional health. Europe, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 49 papers, 6 of them syntheses that pooled it.
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Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
49 citing papers in PubMed, 6 syntheses or guidelines pooled it.
- Life Course Trajectories of Body Mass Index and Risk of Cancer in Adulthood: Systematic Review and Meta-Analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2026Pooled it
- Adiposity and cancer: systematic review and meta-analysis.Nature metabolism · 2026Pooled it
- Body mass index and multiple myeloma: a systematic review and dose-response meta-analysis of prospective cohort studies.BMC cancer · 2026Pooled it
- Vegetarian and vegan diets and cancer incidence: a systematic review and meta-analysis of prospective studies.European journal of epidemiology · 2026Pooled it
- Association between physical activity and gynecological cancers: a meta-analysis of prospective cohort studies.BMC women's health · 2025Pooled it
- Risk factors for postoperative acute kidney injury after cytoreductive surgery combined with hyperthermic intraperitoneal chemotherapy: a meta-analysis and systematic review.World journal of surgical oncology · 2025Pooled it
- Intragastric Balloon Treatment Enhances Weight Maintenance Adjunct to Low-Energy Diet and Group-Based Cognitive Behavioural Therapy: A Randomized Controlled Trial.Diabetes, obesity & metabolism · 2026Trial
- Economic Burden of Overweight and Obesity in Sweden: Current Estimates and Future Projections.Diabetes, obesity & metabolism · 2026Article
- Anthropometric factors, physical activity, and the risk of soft tissue sarcoma: a case-control study.European journal of cancer prevention : the official journal of the European Cancer Prevention Organisation (ECP) · 2026Article
- Population scale analysis reveals gut microbiome diversity and functional shifts linked to obesity.iScience · 2026Article
- Energy Balance-Related Factors and Direct Tumor-Adipocyte Contact in Colorectal Cancer: Etiologic Insights from the Population-Based Netherlands Cohort Study.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026Article
- Differential Expression of Human and Bacterial Proteins Reveals Microbiome-Host Crosstalk in Metabolic Disorders.Proteomics. Clinical applications · 2026Article
- Impact of underweight on patients receiving curative-intent anticancer therapy: analysis of a large oncology database in Saudi Arabia.BMC cancer · 2026Observational
- Adiposity and cancer: epidemiology, mechanisms and future perspectives.Nature metabolism · 2026Review
- Abdominal posture biases 3D optical imaging measurements while bioelectrical impedance analysis remains unaffected.Clinical nutrition ESPEN · 2026Article
- Lifestyle and Dietary Behaviors Are Associated with Body Mass Index in Romanian Young Adults.Nutrients · 2026Article
- Associations of Metabolic Phenotypes with Cardiac Structure and Clinical Outcomes: Insights from the UK Biobank.The Journal of clinical endocrinology and metabolism · 2026Article
- New Oxicam Derivatives-Studies of Membrane Interactions, Cytotoxicity, Cyclooxygenase Inhibition and Molecular Docking.Membranes · 2026Article
- Optimal Dietary Patterns for Lower Weight Gain and Risk of Obesity Surrounding Menopause.JAMA network open · 2026Article
- The Relationship Between Obesity, Overweight, and the Prevalence of Depression and Anxiety Among University Students: Evidence from a Nationally Representative Cross-Sectional Study in Greece.Diseases (Basel, Switzerland) · 2026Article
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Authors and funding
26 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Obesity, assessed by body mass index (BMI), is an established risk factor for 13 cancers. We aimed to identify further potential obesity-related cancers and to quantify their association with BMI relative to that of established obesity-related cancers. Methods: Using Cox regression models on 4,142,349 individuals in Sweden (mean age 27.1 years at weight measurement), we calculated hazard ratios (HRs) for the association between BMI and the risk of 122 cancers and cancer subtypes, grouped by topography and morphology. Cancers with a positive association (i.e., HR >1) at an α-level of 0.05 for obesity (BMI ≥30 kg/m Findings: After 100.2 million person-years of follow-up, 332,501 incident cancer cases were recorded. We identified 15 cancers in men and 16 in women as potentially obesity related. These were cancers of the head and neck, gastrointestinal tract, malignant melanoma, genital organs, endocrine organs, connective tissue, and haematological malignancies. Among these, there was evidence of differential associations with BMI between subtypes of gastric cancer, small intestine cancer, cervical cancer, and lymphoid neoplasms (P values for heterogeneity in HRs <0.05). The HR (95% confidence interval) per 5 kg/m Interpretation: This study suggests a large number of potential obesity-related cancers could be added to already established ones. Importantly, the magnitudes of the associations were largely comparable to those of the already established obesity-related cancers. We also provide evidence of specific cancer subtypes driving some associations with BMI. Studies accounting for cancer-specific confounders are needed to confirm these findings. Funding: Swedish Research Council, Swedish Cancer Society, Mrs. Berta Kamprad's Cancer Foundation, Crafoord Foundation, Cancer Research Foundation at the Department of Oncology, Malmö University Hospital, and China Scholarship Council.
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