Evidence map›Paper›PMID 39253598›Full record

ArticleJBMR plus2024

High-fiber diet reduces bone formation but does not affect bone microarchitecture in type 2 diabetes individuals.

Malak Faraj, Giulia Leanza, Johannes Krug, Francesca Cannata, Viola Viola, Biagio Zampogna, Fabrizio Russo, Giuseppe Banfi, Giovanni Lombardi, Gianluca Vadalà and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in JBMR plus, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Trial
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Malak FarajResearch Unit of Endocrinology and Diabetes, Campus Bio-Medico University of Rome, 00128 Rome, Italy.
Giulia LeanzaResearch Unit of Endocrinology and Diabetes, Campus Bio-Medico University of Rome, 00128 Rome, Italy.
Johannes KrugDepartment of Osteology and Biomechanics, University Medical Center Hamburg Eppendorf, 20246 Hamburg, Germany.
Francesca CannataResearch Unit of Endocrinology and Diabetes, Campus Bio-Medico University of Rome, 00128 Rome, Italy.
Viola ViolaResearch Unit of Endocrinology and Diabetes, Campus Bio-Medico University of Rome, 00128 Rome, Italy.
Biagio ZampognaDepartment of Orthopedic and Trauma Surgery, Departmental Faculty of Medicine and Surgery, Campus Bio-Medico University of Rome, 00128 Rome, Italy.
Fabrizio RussoDepartment of Orthopedic and Trauma Surgery, Departmental Faculty of Medicine and Surgery, Campus Bio-Medico University of Rome, 00128 Rome, Italy.
Giuseppe BanfiLaboratory of Experimental Biochemistry and Molecular Biology, IRCCS Ospedale Galeazzi-Sant'Ambrogio, 20157 Milan, Italy.
Giovanni LombardiLaboratory of Experimental Biochemistry and Molecular Biology, IRCCS Ospedale Galeazzi-Sant'Ambrogio, 20157 Milan, Italy.
Gianluca VadalàDepartment of Orthopedic and Trauma Surgery, Departmental Faculty of Medicine and Surgery, Campus Bio-Medico University of Rome, 00128 Rome, Italy.
Laura MangiaviniLaboratory of Experimental Biochemistry and Molecular Biology, IRCCS Ospedale Galeazzi-Sant'Ambrogio, 20157 Milan, Italy.
Rocco PapaliaDepartment of Orthopedic and Trauma Surgery, Departmental Faculty of Medicine and Surgery, Campus Bio-Medico University of Rome, 00128 Rome, Italy.
Vincenzo DenaroDepartment of Orthopedic and Trauma Surgery, Departmental Faculty of Medicine and Surgery, Campus Bio-Medico University of Rome, 00128 Rome, Italy.
Björn BusseDepartment of Osteology and Biomechanics, University Medical Center Hamburg Eppendorf, 20246 Hamburg, Germany.
Nicola NapoliResearch Unit of Endocrinology and Diabetes, Campus Bio-Medico University of Rome, 00128 Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bone fragility is a recognized complication of type 2 diabetes mellitus (T2DM), increasing patient morbidity. Thus, the development of an effective intervention to prevent diabetic bone fragility is urgently needed. As lifestyle intervention represents an effective option for diabetes management, it may have an impact on bone health. While studies have shown a beneficial effect of dietary fiber in T2DM management, its effect on bone health is still unclear. Thus, we investigated the impact of a high-fiber diet on bone and glucose control in men and women with T2DM. Forty-five T2DM patients (HbA1c: 6.5% ± 0.49%, age: 74 ± 7.29 yr) scheduled for hip arthroplasty were randomly assigned to follow a high-fiber diet (38 g/day) or to make no diet changes for 12 wk. Interestingly, BMI decreased by 4% (

Indexed as

bone microarchitecturebone turnoverglucose controlhigh-fiber diettype 2 diabetesWnt signaling

Identifiers

PMID39253598
PMCPMC11382141

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.