Evidence map›Paper›PMID 39253382›Full record

ArticleFrontiers in pharmacology2024

Junjun Mao, Feifei Yu, Weiwei Qin, Guixian She, Yi Rong, Zhuohan Hu, Mingkang Zhong

Abstract read
In one paragraph

Article in Frontiers in pharmacology, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Junjun Mao *Department of Pharmacy, Huashan Hospital, Fudan University, Shanghai, China.
Feifei Yu *Vigonvita Life Sciences Co. Ltd., Suzhou, China.
Weiwei QinDepartment of Pharmacy, Huashan Hospital, Fudan University, Shanghai, China.
Guixian SheResearch institute for liver diseases (Shanghai) Co. Ltd., Shanghai, China.
Yi RongResearch institute for liver diseases (Shanghai) Co. Ltd., Shanghai, China.
Zhuohan HuResearch institute for liver diseases (Shanghai) Co. Ltd., Shanghai, China.
Mingkang ZhongDepartment of Pharmacy, Huashan Hospital, Fudan University, Shanghai, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: The metabolism- and transporter-based drug-drug interactions (DDIs) between mycophenolate mofetil (MMF) and co-administered medications may be key factors for the high individual variability in MMF exposure. This study systematically assessed the influence of co-medications on the mycophenolic acid (MPA) pharmacokinetic (PK) process Methods: Based on a previous study, we hypothesized that there are three main DDI pathways affecting MMF PK Results: The Conclusion: These identified factors may contribute to the high inter-individual variability in MMF exposure and facilitate further development of mechanistic MMF PK models and individualized therapies.

Indexed as

cyclosporinedrug-drug interactionmycophenolate mofetilprednisolonesalvia miltiorrhiza

Identifiers

PMID39253382
PMCPMC11381307

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.