ArticleWorld journal of critical care medicine2024
Optic nerve sheath diameters in nontraumatic brain injury: A scoping review and role in the intensive care unit.
Article in World journal of critical care medicine, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed.
- Preliminary Evaluation of Preoperative Optic Nerve Sheath Diameter and CT Mass Effect in Relation to Pre-Excision Invasive Intracranial Pressure During Intracranial Tumor Surgery.Journal of clinical medicine · 2026Article
- Optic Nerve Sheath Diameter as a Prognostic Tool for Mortality in Intensive Care Unit Patients.Cureus · 2026Article
- Optic nerve sheath diameter for prediction of intracranial hypertension after ischemic sTrokE - The ONSITE study.European stroke journal · 2026Article
- Prognostic Value of Ultrasonographic Optic Nerve Sheath Diameter in Patients with Sepsis in the Intensive Care Unit: A Prospective Observational Study.International journal of general medicine · 2026Article
- Point-of-care ultrasonography for detecting raised intracranial pressure through optic nerve sheath diameter in non-traumatic headache patients.World journal of radiology · 2025Review
- Optic nerve sheath diameter for prediction of intracranial hypertension after ischemic sTrokE - The ONSITE study.European stroke journal · 2025Article
- Application of ultrasound measurement of optic nerve sheath diameter to guide hyperosmolar therapy in children with intracranial hypertension.Frontiers in pediatrics · 2025Article
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Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundNeuromonitoring in medical intensive care units is challenging as most patients are unfit for invasive intracranial pressure (ICP) modalities or unstable to transport for imaging. Ultrasonography-based optic nerve sheath diameter (ONSD) is an attractive option as it is reliable, repeatable and easily performed at the bedside. It has been sufficiently validated in traumatic brain injury (TBI) to be incorporated into the guidelines. However, currently the data for non-TBI patients is inconsistent for a scientific recommendation to be made.
aimTo compile the existing evidence for understanding the scope of ONSD in measuring ICP in adult non-traumatic neuro-critical patients.
methodsPubMed, Google Scholar and research citation analysis databases were searched for studies in adult patients with non-traumatic causes of raised ICP. Studies from 2010 to 2024 in English languages were included.
resultsWe found 37 articles relevant to our search. The cutoff for ONSD in predicting ICP varied from 4.1 to 6.3 mm. Most of the articles used cerebrospinal fluid opening pressure followed by raised ICP on computed tomography/magnetic resonance imaging as the comparator parameter. ONSD was also found to be a reliable outcome measure in cases of acute ischaemic stroke, intracerebral bleeding and intracranial infection. However, ONSD is of doubtful utility in septic metabolic encephalopathy, dysnatremias and aneurysmal subarachnoid haemorrhage.
conclusionONSD is a useful tool for the diagnosis of raised ICP in non-traumatic neuro-critically ill patients and may also have a role in the prognostication of a subset of patients.
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