Evidence map›Paper›PMID 39253254›Full record

ArticleHeliyon2024

The relationship between semen quality in male infertility clinic patients and bisphenol A：A Chinese cross-sectional study.

Zhiqiang Tian, Zhiwen He, QingQuan Zhang, Ling Ding, Li Song, Ruimin Ren, Kai Tan, Shifu Cao, JinTao Wang, Baolong Pan

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Zhiqiang TianShanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, 030032, China.
Zhiwen HeSchool of Management, Shanxi Medical University, South Xinjian Road, Taiyuan, 030001, China.
QingQuan ZhangSchool of Management, Shanxi Medical University, South Xinjian Road, Taiyuan, 030001, China.
Ling DingSchool of Public Health, Shanxi Medical University, South Xinjian Road, Taiyuan, 030001, China.
Li SongSchool of Public Health, Shanxi Medical University, South Xinjian Road, Taiyuan, 030001, China.
Ruimin RenShanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Third Hospital of Shanxi Medical University, Taiyuan, 030032, China.
Kai TanSchool of Management, Shanxi Medical University, South Xinjian Road, Taiyuan, 030001, China.
Shifu CaoSchool of Health Management, Shanxi Technology and Business College, Taiyuan, 030036, China.
JinTao WangSchool of Public Health, Shanxi Medical University, South Xinjian Road, Taiyuan, 030001, China.
Baolong PanSixth Hospital of Shanxi Medical University, General Hospital of Tisco, Taiyuan, 030008, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bisphenol A (BPA) is a growing concern as an endocrine-disrupting chemical due to its adverse health effects. However, the association between BPA and sperm quality in adult human males remains unclear. The aim of this study was to assess the daily life exposure level of BPA and analyze its correlation with sperm quality in males. Patients who sought treatment in Chinese infertility clinics between May and October 2023 were selected as study subjects. We determined participants' serum BPA content using high-performance liquid chromatography. Sperm count and motility were assessed using a computer-aided sperm analysis system, while sperm morphology was analyzed using an improved Papanicolaou stain. A total of 405 participants, averaging 33.01 ± 5.44 years old, were included. We observed low semen quality among participants in infertility clinics. Principal component analysis was performed for each semen quality index, and three principal components reflecting sperm motility, count, and morphology were extracted. The participants' mean serum BPA level was 6.96 ng/mL. Negative correlations were observed between serum BPA content and total sperm count, sperm density, forward motility rate, and non-forward motility rate. A positive correlation was found between the non-motile sperm rate and the head deformity rate. Morphological abnormalities were the predominant adverse effects observed. Despite low daily life BPA exposure, long-term low-dose exposure in the general population may damage semen quality. This study provides a scientific basis for managing health risks associated with BPA exposure.

Indexed as

BPA exposureCross-sectional studyEndocrine-disrupting chemicalEnvironmental estrogen-like compoundPlastic pollutionSperm morphology

Identifiers

PMID39253254
PMCPMC11381587

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