ReviewHeliyon2024
Hydrolyzed collagen: Exploring its applications in the food and beverage industries and assessing its impact on human health - A comprehensive review.
Review in Heliyon, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
24 citing papers in PubMed.
- Low-Molecular-Weight Salmon Collagen Peptides Promote Extracellular Matrix Gene (ECM) Expression in BJ Fibroblasts.International journal of molecular sciences · 2026Article
- Bioactive Peptides from Animal By-Products: Production, Functional Evidence and Food Applications.Foods (Basel, Switzerland) · 2026Review
- Effects of Alcalase and Pepsin Hydrolysis on Gel Forming Behavior and Technological Properties of Porcine Skin Gelatin.Gels (Basel, Switzerland) · 2026Article
- Article
- Reformulation of Emulsion-Type Pork Sausage Using Collagen and Plasma Proteins as Soy Protein Substitutes for Soy-Free Product Development.Gels (Basel, Switzerland) · 2026Article
- Effect of Gelatin-Peptide Complex from Sturgeon Skin on Behavioral, Antioxidant, and Neuroprotective Functions in D-Galactose-Induced Aging Mice: Thermal Degradation vs. Enzymatic Hydrolysis.Foods (Basel, Switzerland) · 2026Article
- Control of immunogenic responses of microorganism-synthesized biopolymers for 3D bioprinting tissue engineering and regenerative medicine.Bioactive materials · 2026Review
- Hydrolyzed Collagen from Salmon Skin Mitigates L-NAME-Induced Hypertension in Rats by Attenuating Oxidative Stress and Inflammation and Improving Vascular Remodeling.International journal of molecular sciences · 2026Article
- High-Protein Hydrogels Composed of Pea-Collagen Protein and κ-Carrageenan for the Dysphagia Diet.Journal of food science · 2026Article
- Ethosomal Nanocarriers for Hydrophilic Peptide Encapsulation: Formulation Optimization, Stability, and In Vitro Release Performance.Molecules (Basel, Switzerland) · 2026Article
- Fermented Gallus gallus foot keratin-bone composites as peptide-mineral concentrate for aquafeed: ratio-dependent proximate compositional data.BMC research notes · 2026Article
- Natural Bio-Sourced Additives for Bread Technology Improvement and Highly Nutritive Products.Foods (Basel, Switzerland) · 2026Article
- Versatility of Collagen as a Natural Biopolymer for Biomedical, Food, and Cosmetic Applications.Current protein & peptide science · 2026Review
- Inner beauty supplement label information cues, consumer trust, and purchase intentions: cross-sectional evidence from South Korean consumers.Frontiers in psychology · 2026Article
- Beyond Side Effect: Immuno-Ethical Risk Analysis of Animal-Derived Ingredients in Pharmaceuticals.Risk management and healthcare policy · 2026Review
- Article
- Comparative Study of Collagen Gels Extracted from Different Sources.Gels (Basel, Switzerland) · 2025Article
- Biocompatibility Evaluation of Porcine-Derived Collagen Sheets for Clinical Applications: In Vitro Cytotoxicity, In Vivo Sensitization, and Intracutaneous Reactivity Studies.Journal of functional biomaterials · 2025Article
- Mechanical Reinforced and Self-healing Hydrogels: Bioprinted Biomimetic Methacrylated Collagen Peptide-Xanthan Gum Constructs for Ligament Regeneration.Advanced healthcare materials · 2025Article
- A Comprehensive Review on the Valorization of Bioactives from Marine Animal By-Products for Health-Promoting, Biofunctional Cosmetics.Marine drugs · 2025Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hydrolyzed collagen (HC) consists of many small and low-molecular-weight amino acid chains (3-6 kDa) that can be produced either in basic or acidic media through enzymatic activity. This review details the sources of hydrolyzed collagen, its biosynthesis and its uses in the food industry, as well as its production process and beneficial health effects. HC can be extracted from a variety of sources, during which acetic acid is used for the extraction of collagen type I from bovine, porcine, marine, chicken, and fish cartilage. An enzymatic treatment combined with an acidic treatment has shown more efficient extraction results. Because of its properties, it is frequently employed in the food industry since it improves sensorial qualities, as well as in the cosmetic industry as a functional component in face and body cream because of its moisturizing properties. It is also used in the pharmaceutical development of antioxidant supplements often combined with hyaluronic acid and vitamin C. HC has an excellent therapeutic effect on osteoporosis and osteoarthritis, where a daily dose of 12 g enhances pain symptoms and contributes to bone health. It also increases mineral density and protects articular cartilage. This review presents the structure and properties of hydrolyzed collagen, which mainly consists of the amino acids glycine, proline and hydroxyproline in a triple helix, its extraction process and its sources, as well as its applications. In particular, the creation of Enzymatic Membrane Reactor allows the production of HC with different molecular weight distributions, allowing wider application.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.