Evidence map›Paper›PMID 39252982›Full record

ArticleBrain, behavior, & immunity - health2024

Sex differences in the roles of nicotine use and puberty on youth C-reactive protein levels: Effects above and beyond adversity.

Holly T Pham, Stephanie T Lanza, Eric D Claus, Christine M Heim, Jennie G Noll, Chad E Shenk, Hannah M C Schreier

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Brain, behavior, & immunity - health, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Holly T PhamDepartment of Psychology, 239 Moore Building, The Pennsylvania State University, University Park, PA, 16802, United States.
Stephanie T LanzaDepartment of Biobehavioral Health, 219 Biobehavioral Health Building, The Pennsylvania State University, University Park, PA, 16802, United States.
Eric D ClausDepartment of Biobehavioral Health, 219 Biobehavioral Health Building, The Pennsylvania State University, University Park, PA, 16802, United States.
Christine M HeimCharité - Universitätsmedizin Berlin, Corporate Member of Freie Universität Berlin and Humboldt-Universität zu Berlin, Institute of Medical Psychology, Berlin, Germany.
Jennie G NollDepartment of Psychology and Mount Hope Family Center, University of Rochester, Rochester, NY, United States.
Chad E ShenkDepartment of Human Development and Family Studies, The Pennsylvania State University, University Park, PA, 16802, United States.
Hannah M C SchreierDepartment of Biobehavioral Health, 219 Biobehavioral Health Building, The Pennsylvania State University, University Park, PA, 16802, United States.

Funding

STRATIFIED CLUSTER RANDOMIZED TRIAL (SCRT) OF A CLINICAL DECISION RULE (CDR) FOR ABUSIVE HEAD TRAUMA (AHT)P50HD089922 · NICHD · PENNSYLVANIA STATE UNIVERSITY, THE · PI Hannah Milena Caroline Schreier · 2017 to 2026
$16.9M
Child maltreatment and cardiovascular disease risk: examining psychosocial and immunological pathways in a prospective, longitudinal cohortR01HL158577 · NHLBI · PENNSYLVANIA STATE UNIVERSITY, THE · PI SCHREIER, HANNAH MILENA CAROLINE · 2022 to 2025
$2.4M
NHLBI NIH HHS R01 HL158577NICHD NIH HHS P50 HD089922
6 · The paper itself

Abstract

Inflammation likely mediates associations between nicotine use and negative health outcomes. Sex differences have been observed in nicotine use-inflammation links, and physiological processes during puberty might allow for these differences to arise. In this cross-sectional study of 498 youth (ages 8-13, 52% girls, 77% with history of child maltreatment (CM) investigation), sex-differentiated associations between self-reported nicotine use and high-sensitivity C-reactive protein (hs-CRP) were explored. Additionally, self-reported pubertal stage was investigated as a moderator of such nicotine use-hs-CRP links. Hierarchical generalized estimating equation models were adjusted for a wide range of adversity effects: CM investigation history derived from state records, self- and caregiver-report of traumatic life events, adversity-related demographic risk factors (i.e., identification with historically marginalized racial and ethnic groups, household income), and other characteristics that may influence the variables of interest (e.g., medication use, age, body mass index). Nicotine use had a negative main effect on hs-CRP among boys (β = -0.50,

Indexed as

AdversityC-reactive proteinHigh-risk youthInflammationNicotine usePubertal stagePubertySex differences

Identifiers

PMID39252982
PMCPMC11381809

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.