Evidence map›Paper›PMID 39252917›Full record

ArticlemedRxiv : the preprint server for health sciences2024

An updated molecular diagnostic for surveillance of

Samantha G Palace, Jordan A Reyes, Eric Neubauer Vickers, Aishani V Aatresh, Wei Shen, Zamin Iqbal, Yonatan H Grad

Abstract readPreprint
In one paragraph

Article in medRxiv : the preprint server for health sciences, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Samantha G PalaceDepartment of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, MA, USA.ORCID 0000-0002-7849-8078
Jordan A ReyesDepartment of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, MA, USA.ORCID 0009-0003-4983-6378
Eric Neubauer VickersDepartment of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, MA, USA.ORCID 0009-0005-7305-897X
Aishani V AatreshCenter for Communicable Disease Dynamics, Harvard T. H. Chan School of Public Health, Boston, MA, USA.ORCID 0000-0002-9774-2435
Wei ShenEuropean Molecular Biology Laboratory - European Bioinformatics Institute, Hinxton, UK.ORCID 0000-0002-8099-8258
Zamin IqbalMilner Centre for Evolution, University of Bath, UK.ORCID 0000-0001-8466-7547
Yonatan H GradDepartment of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, MA, USA.ORCID 0000-0001-5646-1314

Funding

The Graduate Program in Tropical Infectious Diseases (GPiTID)T32AI049928 · NIAID · HARVARD UNIVERSITY (SCH OF PUBLIC HLTH) · PI Flaminia Catteruccia, Phyllis J. Kanki · 2001 to 2026
$5.0M
Genomics approaches to elucidating pathways to antibiotic resistance in Neisseria gonorrhoeaeR01AI132606 · NIAID · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI Yonatan H Grad · 2017 to 2026
$3.8M
Identification and analysis of compensatory mutations that support the evolution of antibiotic resistance in Neisseria gonorrhoeaeR01AI153521 · NIAID · HARVARD UNIVERSITY D/B/A HARVARD SCHOOL OF PUBLIC HEALTH · PI GRAD, YONATAN H, JERSE, ANN E. · 2020 to 2024
$3.7M
NIAID NIH HHS R01 AI132606NIAID NIH HHS R01 AI153521NIAID NIH HHS T32 AI049928
6 · The paper itself

Abstract

Doxycycline post-exposure prophylaxis (doxy-PEP) for sexually transmitted bacterial infections reduces the risk of syphilis and chlamydia, but effectiveness against gonorrhea is variable, likely attributable to varying resistance rates. As doxy-PEP is incorporated into clinical practice, an urgent unanswered question is whether increased doxycycline use will drive tetracycline-class resistance in

Identifiers

PMID39252917
PMCPMC11383510

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.