Evidence map›Paper›PMID 39252871›Full record

ArticleDiabetes, metabolic syndrome and obesity : targets and therapy2024

Combination of Waist Circumference and Circulating Levels of IGFBP-2 as a Simple Screening Tool for Early Detection of Metabolic Dysfunction-Associated Steatotic Liver Disease.

Chloé Rauzier, Dominic J Chartrand, Natalie Alméras, Isabelle Lemieux, Eric Larose, Patrick Mathieu, Philippe Pibarot, Benoît Lamarche, Caroline Rhéaume, Paul Poirier and 2 more

Abstract read
In one paragraph

Article in Diabetes, metabolic syndrome and obesity : targets and therapy, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Chloé RauzierCentre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec (IUCPQ) - Université Laval, Québec, QC, Canada.
Dominic J ChartrandCentre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec (IUCPQ) - Université Laval, Québec, QC, Canada.
Natalie AlmérasCentre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec (IUCPQ) - Université Laval, Québec, QC, Canada.ORCID 0000-0002-4660-2299
Isabelle LemieuxCentre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec (IUCPQ) - Université Laval, Québec, QC, Canada.
Eric LaroseCentre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec (IUCPQ) - Université Laval, Québec, QC, Canada.
Patrick MathieuCentre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec (IUCPQ) - Université Laval, Québec, QC, Canada.
Philippe PibarotCentre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec (IUCPQ) - Université Laval, Québec, QC, Canada.
Benoît LamarcheCentre Nutrition, santé et société (NUTRISS), Institut sur la nutrition et les aliments fonctionnels (INAF), Université Laval, Québec, QC, Canada.
Caroline RhéaumeCentre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec (IUCPQ) - Université Laval, Québec, QC, Canada.
Paul PoirierCentre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec (IUCPQ) - Université Laval, Québec, QC, Canada.
Jean-Pierre DesprésCentre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec (IUCPQ) - Université Laval, Québec, QC, Canada.
Frédéric PicardCentre de recherche de l'Institut universitaire de cardiologie et de pneumologie de Québec (IUCPQ) - Université Laval, Québec, QC, Canada.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Optimal non-invasive biomarkers for metabolic dysfunction-associated steatotic liver disease (MASLD) remain elusive, especially in the detection of early stages. This study tested in an asymptomatic cohort of 171 men (49.2 ± 8.6 years) and 131 women (51.8 ± 8.5 years) whether waist circumference (WC) and circulating levels of insulin-like growth factor-binding protein 2 (IGFBP-2) could identify individuals with liver fat >5% as assessed by magnetic resonance spectroscopy. Participants with high WC (> 85 or 90 cm for women and men, respectively) and low IGFBP-2 (< 260 or 230 ng/mL for women and men, respectively) were characterized by a higher risk of having MASLD (46.3%,

Indexed as

biomarkerhepatic fathumansinsulin-like growth factor-binding protein 2metabolic dysfunction-associated steatotic liver diseasenon-invasiveplasmawaist circumference

Identifiers

PMID39252871
PMCPMC11382664

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.