Evidence map›Paper›PMID 39252861›Full record

ArticleContemporary clinical trials communications2024

The neurobehavioural effects of cannabidiol in alcohol use disorder: Study protocol for a double-blind, randomised, cross over, placebo-controlled trial.

Tristan P Hurzeler, Warren Logge, Joshua Watt, Marilena M DeMayo, Anastasia Suraev, Iain S McGregor, Paul S Haber, Kirsten C Morley

Abstract read
In one paragraph

Article in Contemporary clinical trials communications, 2024. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Trial
  2. Trial
  3. Article
  4. Review
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Tristan P HurzelerUniversity of Sydney, Faculty of Medicine and Health, Sydney Medical School, NSW, Australia.
Warren LoggeEdith Collins Centre for Translational Research, Royal Prince Alfred Hospital, NSW, Australia.
Joshua WattUniversity of Sydney, Faculty of Medicine and Health, Sydney Medical School, NSW, Australia.
Marilena M DeMayoDepartment of Radiology and Department of Psychiatry, University of Calgary, Calgary, AB, Canada.
Anastasia SuraevUniversity of Sydney, Lambert Initiative for Cannabinoid Therapeutics, Sydney, NSW, Australia.
Iain S McGregorUniversity of Sydney, Lambert Initiative for Cannabinoid Therapeutics, Sydney, NSW, Australia.
Paul S HaberUniversity of Sydney, Faculty of Medicine and Health, Sydney Medical School, NSW, Australia.
Kirsten C MorleyUniversity of Sydney, Faculty of Medicine and Health, Sydney Medical School, NSW, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Current treatments for alcohol use disorders (AUD) have limited efficacy. Recently, Cannabidiol (CBD) has been examined in a multitude of clinical settings. Preclinical and clinical results suggest that CBD might be particularly well suited for the treatment of AUD and may reduce alcohol cue and stress-induced craving and alcohol seeking. This study aims to investigate this new pharmacotherapy with a particular focus on neurobiological and physiological indicators of craving.

Indexed as

Alcohol dependenceAlcohol use disorderCannabidiolfMRIMechanismsNeuroimagingPsychophysiology

Identifiers

PMID39252861
PMCPMC11382041

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.